[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"blog-post-dorsal-fat-reduction-in-pigs-nature-has-the-solution-en":3,"blog-related-dorsal-fat-reduction-in-pigs-nature-has-the-solution-en":62,"blog-popular-single-en":289,"blog-categories-single-en":517,"blog-tags-single-en":538,"responsive-image-[object Object]":13,"blog-section-posts-en":600,"menu-navbar-en":604,"social-links-en":730,"menu-footer-en":750,"available-locales":852},{"data":4},{"id":5,"title":6,"slug":7,"alternate_slugs":8,"summary":9,"content":10,"meta_title":11,"meta_description":12,"focus_keyword":13,"featured_image":14,"thumbnail_image":35,"published_at":50,"category":51,"categories":55,"tags":61},61,"Dorsal fat reduction in pigs: nature has the solution","dorsal-fat-reduction-in-pigs-nature-has-the-solution",{"en":7},"Pig farming is constantly changing. Since its technification in the 1970s, new knowledge and technologies are constantly being added to the farm routine.","\n\u003Cp>\u003Cstrong>\u003Cbr>Jose Antonio Rivera1; Felipe Horta1; Homero Borin2\u003C\u002Fstrong>\u003Cbr>\u003Cstrong>1. Technical & Marketing Manager – Nuproxa Switzerland\u003C\u002Fstrong>\u003Cbr>\u003Cstrong>2. Technical Director – Nuproxa Switzerland\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>INTRODUCTION\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>Pig farming is constantly changing. Since its technification in the 1970s, new knowledge and technologies are constantly being added to the farm routine.\u003C\u002Fp>\n\n\n\n\u003Cp>The technification of pig farming started in Europe in the 1970s (SESTI, L.A.C.; SOBESTIANSKY, 1998), through intensification of the activity by adopting management that sought efficiency in terms of producing more quantity (kg of meat) with fewer resources (space, time, labor, feed, etc.).\u003C\u002Fp>\n\n\n\n\u003Cp>Obtaining an excellent productivity with continuous improvements and identifying the limiting causes for these indices to be reached became fundamental for producers and technicians linked to pig farming. Thus, indices such as feed conversion ratio (FC), daily weight gain (DWG), carcass yield (CR), absence of diseases and low mortality in all phases of production have always been considered critical in modern pig farming.\u003C\u002Fp>\n\n\n\n\u003Cp>In these phases it is desired that the pig gains the maximum weight in the shortest possible time, consuming the minimum amount of feed (MORÉS; AMARAL, 2001). Accelerated weight gain means achieving slaughter weight in the shortest possible time and, in this way, the producer achieves a return on his investment in the shortest possible time (VOS; DEWEY; FRIENDSHIP, 2000).\u003C\u002Fp>\n\n\n\n\u003Cp>However, quantity is no longer the only factor to consider. The quality of the meat and the way the animals are reared (and fed) became decisive factors for consumers when choosing a product in the market. All this within the legal framework of each country, which in many cases limits or prohibits the use of practices\u002Fproducts that could be considered unethical.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>MEAT\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>The consumer considers the following as indicators of pork quality: appearance, color, smell, taste, tenderness, amount of fat, etc.\u003Cbr>Pigs accumulate fat under the skin in the dorsal region. This deposition expressed in millimeters of thickness is a criterion to differentiate carcasses as lean or fatty. The market demands leaner carcasses with less back fat. To achieve this, Ractopamine, a β-adrenergic that reverses the rate of fat and muscle deposition in pigs close to slaughter, was used for a long time, resulting in less fat deposition at this stage and greater availability of nutrients for muscle formation. However, the use of this molecule is currently banned in the European market and the industry is looking for alternatives to its use.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>CHOLINE METABOLITES\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>Choline is commonly supplemented in monogastric diets because it is an essential component of the cell membrane phospholipids (BATTAGLIA; SCHIMMEL, 1997), participates in liver metabolism by preventing fat accumulation in the carcass (BEST et al., 1932), is a precursor of acetylcholine (DALE; DUDLEY 1929) and is essential for a balanced and functional methylation cycle. A properly functioning methylation cycle processes methionine through adenylation to S-adenosylmethionine (SAM), which is the methyl donor in more than 50 different reactions, including DNA methylation, creatine synthesis and Phosphatidylcholine synthesis (BERTOLO; MCBREAIRTY, 2013).\u003C\u002Fp>\n\n\n\n\u003Cp>The methylation cycle also provides a source of phospholipids for use in membrane structures, as well as lipoproteins important for fat (energy) metabolism. Choline not only provides the choline moiety for phospholipid and lipoprotein synthesis, but also assists in the regeneration of methionine, thus saving methionine for protein synthesis. As such, choline supplementation ultimately supports the optimal functioning of fat and protein metabolism.\u003C\u002Fp>\n\n\n\n\u003Cp>The suggested minimum level of choline in pig diets is around 300mg\u002Fkg, but there are conditions of raw material, animal life stage, digestion and metabolization that justify its use, or that of its secondary metabolites, at higher densities (RAVINDRAN et al., 2016).\u003Cbr>When choline is ingested, it is metabolized to phosphatidylcholine, the molecule responsible for choline’s known effects. Phosphatidylcholine also plays an emulsifying role and activates cell receptors to mobilize fat.\u003C\u002Fp>\n\n\n\n\u003Cp>It has been shown in research that \u003Cstrong>Natu-B4®\u003C\u002Fstrong> is more effective than choline chloride in achieving levels of phosphatidylcholine capable of performing the functions attributed to choline. One of the reasons for \u003Cstrong>Natu-B4®\u003C\u002Fstrong>‘s ability to completely replace the presence of choline chloride, and at much lower doses, is that its phospholipid constituents (Phosphatidylcholine and other phytoactive phospholipid conjugates) bind to peroxisome proliferator-activated receptors (PPARs), primarily liver PPARα (Figure 1).\u003C\u002Fp>\n\n\n\n\u003Cp>PPARα are nuclear receptors that are related to the production of the hormone adiponectin in a directly proportional manner, i.e. the more PPARα receptor activation, the more adiponectin production. Adiponectin is an adipokine protein involved in several metabolic functions, such as lipid and glucose metabolism, glucose utilization and lipogenesis.\u003C\u002Fp>\n\n\n\n\u003Cp>To be activated, this adiponectin must bind to AdipoR1 and AdipoR2 receptors, expressed in insulin-sensitive tissues such as skeletal muscle, liver, pancreas and adipose tissue, where it increases AMP-dependent protein kinase (AMPK) activity, promoting fatty acid oxidation and the entry of glucose into tissues.\u003C\u002Fp>\n\n\n\n\u003Cp>In addition, adiponectin has a direct effect on the regulation of metabolic pathways in the liver, optimizing nutrient utilization and weight gain. It functions to remove fat from areas of fat accumulation (mainly liver in poultry and subcutaneous dorsum in pigs), to catabolize fat and to make nutrients available for other tissue formation.\u003C\u002Fp>\n\n\n\n\u003Cp>Binding of adiponectin to its receptors increases the activity of AMP-dependent protein kinase (AMPK) and peroxisome proliferator-activated receptor alpha (PPAR-alpha), promoting fatty acid\u003C\u002Fp>\n\n\n\n\u003Cdiv class=\"wp-block-image\">\u003Cfigure class=\"aligncenter\">\u003Cimg src=\"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F01\u002F-product_main_image-yhUcD1dv.webp\" srcset=\"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F01\u002F-product_main_image-yhUcD1dv-small.webp 400w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F01\u002F-product_main_image-yhUcD1dv.webp 651w\" alt=\"BioCholine® - Imagem Principal do Produto\" width=\"651\" height=\"320\" loading=\"lazy\">\u003C\u002Ffigure>\u003C\u002Fdiv>\n\n\n\n\u003Cp>\u003Cem>Figure 1 Choline metabolism. \u003Cstrong>Natu-B4®\u003C\u002Fstrong> acts on several metabolic pathways\u003C\u002Fem>\u003C\u002Fp>\n\n\n\n\u003Cp>Thus, the more these receptors are activated (animals supplemented with \u003Cstrong>Natu-B4®\u003C\u002Fstrong> from a young age activate the PPARα receptors earlier and as adults the fat reduction effect is greater), the greater the effect of adiponectin on the animals.\u003C\u002Fp>\n\n\n\n\u003Cp>The mechanisms of action described have been verified by HPLC analysis and metagenomic studies with the product, so these effects are proven and guaranteed exclusively for \u003Cstrong>Natu-B4®\u003C\u002Fstrong>.\u003C\u002Fp>\n\n\n\n\u003Cp>Studies carried out in European and Latin American countries, both in research centers and commercial farms have shown that the use of \u003Cstrong>Natu-B4®\u003C\u002Fstrong> (in the complete absence of choline chloride) not only improves production indices such as weight gain, feed conversion, mortality, but also reduces backfat in pigs close to slaughter; and that this reducing effect is more noticeable the earlier the piglets are supplemented.\u003C\u002Fp>\n\n\n\n\u003Cp>Finally, recent studies show that increasing the dose of \u003Cstrong>Natu-B4®\u003C\u002Fstrong> during the last 4 weeks of pigs’ life optimizes the backfat reducing effect at slaughter.\u003C\u002Fp>\n\n\n\n\u003Cp>We can conclude that the use of \u003Cstrong>Natu-B4®\u003C\u002Fstrong> as the sole source of functional choline metabolites in the diet of pigs is shown to be an alternative to obtain the backfat reducing effect achieved with Ractopamine, increase daily weight gain, carcass yield, decrease feed conversion and mortality, with the additional advantage of not presenting any type of risk, prohibition or withdrawal period, as it is a 100% natural product.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>BIBLIOGRAPHY\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>BATTAGLIA KB, SCHIMMEL RJ. Cell membrane lipid composition and distribution: implications for cell function and lessons learned from photoreceptors and platelets. J Exp Biol. 1997;200:2927–36.\u003Cbr>BERTOLO, R. F.; MCBREAIRTY, L. E. The nutritional burden of methylation reactions. Current Opinion in Clinical Nutrition and Metabolic Care, v. 16, n. 1, p. 102–108, 2013.\u003Cbr>BEST CH, HERSHEY JM, HUNTSMAN M. The effect of lecithine on fat deposition in the liver of the normal rat. J Physiol. 1932;75:56-66.\u003Cbr>DALE HH, DUDLEY HW. The presence of histamine and acetylcholine in the spleen of the ox and the horse. J Physiol. 1929;68:97-123.\u003Cbr>MORÉS, N.; AMARAL, A. L. DO. Patologias associadas ao desmame. CONGRESSO BRASILEIRO DE VETERINÁRIOS ESPECIALISTAS EM SUÍNOS. Anais…Porto Alegre R.S.: Asociação Brasileira de Veterinarios Especialistas em Suínos, 2001\u003Cbr>RAVINDRAN, V. et al. Fats in poultry nutrition: Digestive physiology and factors influencing their utilisation. Animal Feed Science and Technology, v. 213, n. January, p. 1–21, 2016.\u003Cbr>SESTI, L.A.C.; SOBESTIANSKY, J. Aspectos da produtividade. Suinocultura intensiva, v. 388, n. 4, p. 65–90, 1998.\u003Cbr>VOS, L.; DEWEY, C.; FRIENDSHIP, B. Value of pigs by growth rates. American Association of Swine Practitioners. Anais…2000\u003C\u002Fp>\n","Dorsal fat reduction in pigs: nature has the solution - Nuproxa Switzerland Ltd","",null,{"id":15,"filename":16,"path":17,"url":18,"alt_text":19,"title":13,"width":20,"height":21,"webp_url":22,"optimized_url":22,"thumbnail_url":23,"srcset":24,"srcset_webp":25,"responsive_images":26,"processing_status":34},754,"HEADER (1).png","assets\u002F2026\u002F04\u002Fheader-1-69e268793c3e9.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-1-69e268793c3e9.png","Swine farm header with grouped piglets, Nuproxa swine nutrition animal health",1728,326,"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-1-69e268793c3e9.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-1-69e268793c3e9-thumbnail.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-1-69e268793c3e9-thumbnail.png 150w, 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https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-1-69e268793c3e9.webp 1728w",{"large":27,"small":28,"medium":29,"thumbnail":23,"large_webp":30,"small_webp":31,"medium_webp":32,"thumbnail_webp":33},"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-1-69e268793c3e9-large.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-1-69e268793c3e9-small.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-1-69e268793c3e9-medium.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-1-69e268793c3e9-large.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-1-69e268793c3e9-small.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-1-69e268793c3e9-medium.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-1-69e268793c3e9-thumbnail.webp","completed",{"id":36,"filename":37,"path":38,"url":39,"alt_text":40,"title":41,"width":42,"height":43,"webp_url":44,"optimized_url":44,"thumbnail_url":45,"srcset":46,"srcset_webp":47,"responsive_images":48,"processing_status":34},566,"8-conteudo-1.png","assets\u002F2026\u002F03\u002Fcee0ef1d-7615-4522-81d1-8ded77803275.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002Fcee0ef1d-7615-4522-81d1-8ded77803275.png","Piglets nursery plastic slat floor gut health modern swine production Nuproxa nutrition","Dorsal fat reduction in pigs: nature has the solution (thumb)",304,200,"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002Fcee0ef1d-7615-4522-81d1-8ded77803275.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002Fcee0ef1d-7615-4522-81d1-8ded77803275-thumbnail.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002Fcee0ef1d-7615-4522-81d1-8ded77803275-thumbnail.png 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002Fcee0ef1d-7615-4522-81d1-8ded77803275.png 304w","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002Fcee0ef1d-7615-4522-81d1-8ded77803275-thumbnail.webp 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002Fcee0ef1d-7615-4522-81d1-8ded77803275.webp 304w",{"thumbnail":45,"thumbnail_webp":49},"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002Fcee0ef1d-7615-4522-81d1-8ded77803275-thumbnail.webp","2022-03-31T16:07:04+00:00",{"id":52,"name":53,"slug":54,"description":13},33,"Gut Health","gut-health",[56,57],{"id":52,"name":53,"slug":54,"description":13},{"id":58,"name":59,"slug":60,"description":13},80,"Swine","swine",[],{"data":63},[64,141,197,246],{"id":65,"title":66,"slug":67,"alternate_slugs":68,"summary":69,"content":70,"meta_title":71,"meta_description":72,"focus_keyword":13,"featured_image":73,"thumbnail_image":90,"published_at":105,"category":106,"categories":110,"tags":121},44,"Do you still use choline chloride in your production?","do-you-still-use-choline-chloride-in-your-production",{"en":67},"Discover a solution capable of transforming your results! The natural revolution to increase animal profitability and performance Natu-B4™ is not just a total replacement for choline chloride, it is an alternative that exceeds expectations  terms of performance, energy efficiency and sustainability. ​ With over 20 years of application and an extensive list of scientific publications, […]","\n\u003Ch2 class=\"wp-block-heading\" id=\"h-discover-a-solution-capable-of-transforming-your-results\">\u003Cstrong>\u003Cem>Discover a solution capable of transforming your results!\u003C\u002Fem>\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Ch4 class=\"wp-block-heading\" id=\"h-the-natural-revolution-to-increase-animal-profitability-and-performance\">\u003Cstrong>The natural revolution to increase animal profitability and performance\u003C\u002Fstrong>\u003C\u002Fh4>\n\n\n\n\u003Cp>Natu-B4™ is not just a \u003Ca href=\"https:\u002F\u002Fnuproxa.ch\u002Fen\u002FProduct\u002Fnatu-b4\u002F\">total replacement for choline chloride\u003C\u002Fa>, it is an alternative that exceeds expectations  terms of performance, energy efficiency and sustainability. ​\u003C\u002Fp>\n\n\n\n\u003Cp>With over 20 years of application and an extensive list of scientific publications, Natu-B4™ is the choice of producers looking to maximize results without compromising animal health or the environment.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\" id=\"h-do-you-still-use-choline-chloride-in-your-production\">\u003Cstrong>Do you still use choline chloride in your production?\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Ch4 class=\"wp-block-heading\" id=\"h-replace-choline-chloride-with-natu-b4\">\u003Cstrong>Replace choline chloride with Natu-B4™\u003C\u002Fstrong>\u003C\u002Fh4>\n\n\n\n\u003Col class=\"wp-block-list\">\n\u003Cli>\u003Cstrong>Industrial benefit\u003C\u002Fstrong>\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Forget the problems and consequences of hygroscopicity: it is the end of premix caking, reduce excess \u003Cem>carriers \u003C\u002Fem>by reducing premix volume, stocks and transports and thus increasing your competitiveness, reduce crusting in mixers and eliminate vitamin overdosing. \u003C\u002Fli>\n\n\n\n\u003Cli>With Natu-B4™ you can now include your choline source in the premix without fear and thus eliminate a problematic ingredient from your finished feed plant.\u003C\u002Fli>\n\u003C\u002Ful>\n\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Performance and health benefits\u003C\u002Fstrong>\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Natu-B4™ complements the choline present in cereals in an intelligent way, having its greatest potency precisely in the function where cereal choline or choline chloride are less effective: energy metabolism, which makes it the ingredient of choice when we think of a complementary and complete supplementation.\u003C\u002Fli>\n\u003C\u002Ful>\n\u003C\u002Fli>\n\u003C\u002Fol>\n\n\n\n\u003Cp>\u003Cstrong>Better performance:\u003C\u002Fstrong> By stimulating metabolic pathways, Natu-B4™ increases lipid utilization and gluconeogenesis, thereby increasing the amount of metabolizable energy available for animal performance and health, as reflected in GPD, CI, reproductive parameters, etc.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>Reduce fat deposition:\u003C\u002Fstrong> By increasing lipid utilization, \u003Ca href=\"https:\u002F\u002Fnutrinews.com\u002Fen\u002Fdeciphering-natu-b4-a-comprehensive-insight\u002F\">Natu-B4™\u003C\u002Fa> can be applied in a specific protocol to reduce fat deposition in the liver and abdominal cavity of poultry and in the subcutaneous tissue of pigs, avoiding chronic problems resulting from excessive deposition, and potentially improving profitability at the slaughterhouse.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>More results:\u003C\u002Fstrong> By excluding choline chloride, we reduce the intake of chlorine in diets, which reduces the likelihood of metabolic problems resulting from its excess.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\" id=\"h-do-you-still-use-choline-chloride-in-your-production-0\">\u003Cstrong>Do you still use choline chloride in your production? \u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Ch4 class=\"wp-block-heading\" id=\"h-then-you-need-to-know-the-effect-on-animal-performance-of-replacing-choline-chloride-with-natu-b4\">\u003Cstrong>Then you need to know the effect on animal performance of replacing choline chloride with Natu-B4.\u003C\u002Fstrong>\u003C\u002Fh4>\n\n\n\n\u003Cp>Historical differences in weight gain and feed conversion rate between broilers supplemented with Natu-B4™ and choline chloride:\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large\" id=\"NatuB4\">\u003Cimg src=\"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F26c1e9f7-f8c7-46fe-8e80-fa9fd39ca6ef.webp\" srcset=\"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F26c1e9f7-f8c7-46fe-8e80-fa9fd39ca6ef-small.webp 400w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F26c1e9f7-f8c7-46fe-8e80-fa9fd39ca6ef-medium.webp 800w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F26c1e9f7-f8c7-46fe-8e80-fa9fd39ca6ef.webp 1024w\" alt=\"Blog inline image\" width=\"1024\" height=\"559\" loading=\"lazy\">\u003C\u002Ffigure>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large\" id=\"NatuB4\">\u003Cimg src=\"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F695ad22f-99a8-4c44-a64d-c26bc7306572.webp\" srcset=\"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F695ad22f-99a8-4c44-a64d-c26bc7306572-small.webp 400w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F695ad22f-99a8-4c44-a64d-c26bc7306572-medium.webp 800w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F695ad22f-99a8-4c44-a64d-c26bc7306572.webp 1024w\" alt=\"Blog inline image\" width=\"1024\" height=\"559\" loading=\"lazy\">\u003C\u002Ffigure>\n\n\n\n\u003Ch2 class=\"wp-block-heading\" id=\"h-benefit-in-carcass-composition\">\u003Cstrong>Benefit in carcass composition\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>If applied in a specific protocol, Natu-B4™ can significantly modulate the carcass composition of poultry and pigs. \u003C\u002Fp>\n\n\n\n\u003Cp>> Thus, less fat is deposited and more energy is available for muscle development.\u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Up to -2.8 mm of backfat in pigs\u003C\u002Fli>\n\n\n\n\u003Cli>Up to +10% spine depth\u003C\u002Fli>\n\n\n\n\u003Cli>Up to +4.2% % of meat in carcasses\u003C\u002Fli>\n\n\n\n\u003Cli>Up to -16% amount of fat in liver\u003C\u002Fli>\n\n\n\n\u003Cli>Up to -20% relative weight of abdominal fat\u003C\u002Fli>\n\n\n\n\u003Cli>Up to -9% relative liver weight\u003C\u002Fli>\n\n\n\n\u003Cli>Up to 100% reduction of fatty liver syndrome\u003C\u002Fli>\n\u003C\u002Ful>\n\n\n\n\u003Ch2 class=\"wp-block-heading\" id=\"h-effect-on-energy-distribution\">\u003Cstrong>Effect on energy distribution\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>\u003Cstrong>Poultry: \u003C\u002Fstrong>less fat deposition in the liver and abdomen, lower incidence of fatty liver and more energy available for muscle development.\u003C\u002Fp>\n\n\n\u003Cdiv class=\"wp-block-image\">\n\u003Cfigure class=\"aligncenter size-medium\" id=\"Natu-B4\">\u003Cimg src=\"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F14a8f378-ba5a-4774-b67f-e2d990ea7c7a.webp\" srcset=\"\" alt=\"Blog inline image\" width=\"300\" height=\"291\" loading=\"lazy\">\u003Cfigcaption class=\"wp-element-caption\">\u003Cem>1- Agrawal (2012)\u003C\u002Fem>\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\u003Cdiv class=\"wp-block-image\">\n\u003Cfigure class=\"aligncenter size-medium\" id=\"NatuB4\">\u003Cimg src=\"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F272b74b0-6f56-4d76-88cf-34a04b91beff.webp\" srcset=\"\" alt=\"Blog inline image\" width=\"300\" height=\"294\" loading=\"lazy\">\u003Cfigcaption class=\"wp-element-caption\">2-\u003Cem>Le Roux (2015)\u003C\u002Fem>\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\u003Cdiv class=\"wp-block-image\">\n\u003Cfigure class=\"aligncenter size-medium\" id=\"NatuB4\">\u003Cimg src=\"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F4f268a0b-c242-4514-97c4-4a99612b6791.webp\" srcset=\"\" alt=\"Blog inline image\" width=\"300\" height=\"291\" loading=\"lazy\">\u003Cfigcaption class=\"wp-element-caption\">\u003Cem>3 – Agrawal (2012)\u003C\u002Fem>\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\u003Cdiv class=\"wp-block-image\">\n\u003Cfigure class=\"aligncenter size-medium\" id=\"NatuB4\">\u003Cimg src=\"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F35dc3b24-7c20-4f9a-995d-4fb26053f56a.webp\" srcset=\"\" alt=\"Blog inline image\" width=\"300\" height=\"290\" loading=\"lazy\">\u003Cfigcaption class=\"wp-element-caption\">\u003Cem>4 – Agrawal (2012)\u003C\u002Fem>\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\n\u003Cp>\u003Cstrong>Pigs: \u003C\u002Fstrong>Lower subcutaneous fat deposition which means leaner carcasses, greater energy availability for muscle development and higher percentage of meat in carcasses with higher yield of cuts.\u003C\u002Fp>\n\n\n\n\u003Cdiv class=\"wp-block-group is-vertical is-content-justification-center is-layout-flex wp-container-core-group-is-layout-4b2eccd6 wp-block-group-is-layout-flex\">\n\u003Cfigure class=\"wp-block-image size-medium\">\u003Cimg src=\"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002Fe9838fda-2074-4815-8413-f81446c27a22.webp\" srcset=\"\" alt=\"Blog inline image\" width=\"300\" height=\"247\" loading=\"lazy\">\u003C\u002Ffigure>\n\n\n\n\u003Cfigure class=\"wp-block-image size-medium\">\u003Cimg src=\"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F12c21e11-1905-4743-8edf-d51ea75e1409.webp\" srcset=\"\" alt=\"Blog inline image\" width=\"300\" height=\"201\" loading=\"lazy\">\u003C\u002Ffigure>\n\n\n\n\u003Cfigure class=\"wp-block-image size-medium\">\u003Cimg src=\"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F29916252-396a-4597-b83b-0f89cf25ea14.webp\" srcset=\"\" alt=\"Blog inline image\" width=\"300\" height=\"205\" loading=\"lazy\">\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\n\n\u003Ch2 class=\"wp-block-heading\" id=\"h-cost-effective-formula\">\u003Cstrong>Cost-effective formula\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>Natu-B4™ reduces fat deposition in the carcass by converting it into energy for muscle growth and development. \u003C\u002Fp>\n\n\n\n\u003Cp>The amount of metabolizable energy available is known and this value can save energy in the formulation of poultry diets, \u003Ca href=\"https:\u002F\u002Fnutrinews.com\u002Fen\u002Fcan-natu-b4-reduce-the-cost-of-pig-production-2\u002F\">significantly reducing their cost\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\n\u003Cp>Since Natu-B4™ acts in certain metabolic pathways, i.e. after nutrient absorption, it does not compete for substrates with enzymes and emulsifiers, and may even have a complementary or synergistic effect with these additives.\u003C\u002Fp>\n\n\n\n\u003Cp>If you use bicarbonate to balance sodium with a lower chlorine content, by using Natu-B4™ you can reduce its inclusion, increasing common salt and thus reducing costs.\u003C\u002Fp>\n\n\n\n\u003Cp>In addition, the inclusion of Natu-B4™ is in itself more economical than that of choline chloride. This is due to its high potency, which comes from the synergy between several phytoactives, resulting in low inclusion doses. Each kg of Natu-B4™ is equivalent to 4.84 kg of 60% choline chloride.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\" id=\"h-environment\">\u003Cstrong>Environment\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>For every ton of Natu-B4™ applied, we stop using almost 5 tons of petroleum derivatives from a chemical industry. Instead, we use a 100% natural product derived from carbon-fixing plants.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\" id=\"h-are-you-sure-about-this-do-you-still-use-choline-chloride-in-your-production\">\u003Cstrong>Are you sure about this?\u003C\u002Fstrong> \u003Cstrong>Do you still use choline chloride in your production?\u003C\u002Fstrong>\u003C\u002Fh3>\n\n\n\n\u003Ch4 class=\"wp-block-heading\" id=\"h-now-you-re-ready-to-take-your-production-to-the-next-level-with-natu-b4\">\u003Cstrong>Now you’re ready to take your production to the next level with Natu-B4\u003C\u002Fstrong>\u003C\u002Fh4>\n\n\n\n\u003Cp>\u003Ca href=\"https:\u002F\u002Fnuproxa.ch\u002Fen\u002FProduct\u002Fnatu-b4\u002F\">Discover\u003C\u002Fa> how Natu-B4™ can transform your bottom line and make your animal nutrition more efficient and sustainable.\u003Cbr>📩\u003Cstrong> Request a sample or talk to our technical team\u003C\u002Fstrong>: \u003Ca href=\"mailto:products@nuproxa.ch\">products@nuproxa.ch\u003C\u002Fa>\u003Cbr>🌐\u003Cstrong> More information at:\u003C\u002Fstrong> Natu-B4®\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>Natu-B4™: \u003Ca href=\"https:\u002F\u002Fnuproxa.ch\u002Fen\u002FProduct\u002Fnatu-b4\u002F\">Natural, innovative and proven effective\u003C\u002Fa>\u003C\u002Fstrong>\u003C\u002Fp>\n","Do you still use choline chloride in your production? - Nuproxa Switzerland Ltd","Do you still use choline chloride in your production? Natu-B4™ is a high-performance, energy-efficient and sustainable alternative to CC.",{"id":74,"filename":75,"path":76,"url":77,"alt_text":13,"title":13,"width":20,"height":21,"webp_url":78,"optimized_url":78,"thumbnail_url":79,"srcset":80,"srcset_webp":81,"responsive_images":82,"processing_status":34},772,"HEADER (11).png","assets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b-thumbnail.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b-thumbnail.png 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b-small.png 400w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b-medium.png 800w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b-large.png 1200w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b.png 1728w","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b-thumbnail.webp 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b-small.webp 400w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b-medium.webp 800w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b-large.webp 1200w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b.webp 1728w",{"thumbnail":79,"thumbnail_webp":83,"small":84,"small_webp":85,"medium":86,"medium_webp":87,"large":88,"large_webp":89},"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b-thumbnail.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b-small.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b-small.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b-medium.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b-medium.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b-large.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-11-6a1879793fc9b-large.webp",{"id":91,"filename":92,"path":93,"url":94,"alt_text":95,"title":96,"width":97,"height":98,"webp_url":99,"optimized_url":99,"thumbnail_url":100,"srcset":101,"srcset_webp":102,"responsive_images":103,"processing_status":34},517,"Image2-Natu-B4-vs-Chorine-Chloride.png","assets\u002F2026\u002F03\u002Ffe479f62-f948-43f2-aa6c-6bd4c4001efa.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002Ffe479f62-f948-43f2-aa6c-6bd4c4001efa.png","Thumbnail Natu-B4 Nuproxa swine and broilers plant choline replaces choline chloride","Do you still use choline chloride in your production? (thumb)",349,230,"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002Ffe479f62-f948-43f2-aa6c-6bd4c4001efa.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002Ffe479f62-f948-43f2-aa6c-6bd4c4001efa-thumbnail.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002Ffe479f62-f948-43f2-aa6c-6bd4c4001efa-thumbnail.png 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002Ffe479f62-f948-43f2-aa6c-6bd4c4001efa.png 349w","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002Ffe479f62-f948-43f2-aa6c-6bd4c4001efa-thumbnail.webp 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002Ffe479f62-f948-43f2-aa6c-6bd4c4001efa.webp 349w",{"thumbnail":100,"thumbnail_webp":104},"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002Ffe479f62-f948-43f2-aa6c-6bd4c4001efa-thumbnail.webp","2025-02-17T17:37:01+00:00",{"id":107,"name":108,"slug":109,"description":13},42,"News","news",[111,112,116,120],{"id":107,"name":108,"slug":109,"description":13},{"id":113,"name":114,"slug":115,"description":13},48,"Nutrition","nutrition",{"id":117,"name":118,"slug":119,"description":13},63,"Poultry","poultry",{"id":58,"name":59,"slug":60,"description":13},[122,126,130,134,137],{"id":123,"name":124,"slug":125},3,"Animal Feed","animal-feed",{"id":127,"name":128,"slug":129},15,"choline chloride","choline-chloride",{"id":131,"name":132,"slug":133},36,"Natu-B4","natu-b4",{"id":135,"name":114,"slug":136},45,"nutrition-en",{"id":138,"name":139,"slug":140},58,"replace choline chloride","replace-choline-chloride",{"id":138,"title":142,"slug":143,"alternate_slugs":144,"summary":145,"content":146,"meta_title":147,"meta_description":12,"focus_keyword":13,"featured_image":148,"thumbnail_image":166,"published_at":179,"category":180,"categories":184,"tags":196},"Supplementation with natural choline: myth or reality?","supplementation-with-natural-choline-myth-or-reality",{"en":143},"Choline is well known for its nutritional advantages since the 30’s and its supplementation in animal diets is very common, especially for monogastrics.The role of choline in the prevention of problems such as perosis or fatty liver in broilers is well known and its supplementation through the feed is essential, especially for certain phases or breeding conditions.","\n\u003Cp>\u003Cem>By: Hamilton Ida y Sandra Olivera.\u003C\u002Fem>\u003C\u002Fp>\n\n\n\n\u003Cp>Choline is well known for its nutritional advantages since the 30’s and its supplementation in animal diets is very common, especially for monogastrics.The role of choline in the prevention of problems such as perosis or fatty liver in broilers is well known and its supplementation through the feed is essential, especially for certain phases or breeding conditions.\u003C\u002Fp>\n\n\n\n\u003Cp>In recent years, choline supplementation from herbaceous products (BioCholine®) has emerged as an alternative to choline chloride, the standard ingredient used in the animal production industry. The use of natural choline in poultry and pig diets has become more common in markets with high production efficiency and that operate under considerable pressure for cost reduction, such as Brazil, Mexico, Peru, Chile, among others. Currently, vegetal choline is widely used in Latin America, with the potential to grow significantly in Europe.\u003C\u002Fp>\n\n\n\n\u003Cp>This article analyzes this context and points out the reasons of the growth of the use of natural choline as a supplement in animal nutrition replacing choline chloride.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>\u003Cem>Choline and its functions\u003C\u002Fem>\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cem>Choline is an essential nutrient with a vitamin-like action. In specific conditions, its endogenous synthesis may be too low to complete the requirements of food animals. For example, chicks until the third week of age are not able to synthesize sufficient choline to meet their metabolic demand.\u003C\u002Fem>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cem>Many important metabolic processes depend on choline such as:\u003C\u002Fem>\u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\u003Cli>\u003Cem>Synthesis of the phospholipids which are part of the cells membranes;\u003C\u002Fem>\u003C\u002Fli>\u003Cli>\u003Cem>Precursor of the neurotransmitter acetylcholine;\u003C\u002Fem>\u003C\u002Fli>\u003Cli>\u003Cem>Donor of methyl groups in the methionine metabolism;\u003C\u002Fem>\u003C\u002Fli>\u003Cli>\u003Cem>Metabolism of the fats in the liver;\u003C\u002Fem>\u003C\u002Fli>\u003C\u002Ful>\n\n\n\n\u003Cp>Choline is a natural constituent of many raw materials commonly used for the formulation of livestock and pet diets. However, its concentration and bioavailability in these sources can be very variable. For this reason, and in order to guarantee adequate levels to cover the production needs of the different species, feed formulators provide the choline supplementation through the traditional source, choline chloride.\u003C\u002Fp>\n\n\n\n\u003Cp>Choline chloride is chemically synthetized through the reaction between trimethylamine (synthetized from the methanol and ammonium), hydrochloric acid and ethylene oxide. Its cost in formulation is relatively low in comparison with other vitamins. However, there are nutritional, as well as operational disadvantages with this product:\u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\u003Cli>Only 1\u002F3 of the choline is absorbed; the remaining 2\u002F3 are transformed into trimethylamine (TMA) during the digestion by the intestinal flora. The TMA is then absorbed and can affect negatively the hepatic metabolism of the birds and is also known to give a fishy smell to the eggs;\u003C\u002Fli>\u003Cli>Its concentration is low (in general, 60% for the powder and 75% for the liquid), which requires a higher inclusion rate and thus occupies more space in the formula;\u003C\u002Fli>\u003Cli>Choline chloride provides some chloride, which should be taken into account in the electrolyte balance; for example, the excess of chlorine in the diets is associated with metabolic acidosis, which predisposes the broilers to metabolic diseases such as tibial dyschondroplasia (already in the initial stages) and ascitic syndrome;\u003C\u002Fli>\u003Cli>Hygroscopicity and corrosivity – in addition to being unstable and difficult to handle during feed production, choline chloride can increase humidity and cause destruction of vitamins in the premixes and the feeds.\u003C\u002Fli>\u003C\u002Ful>\n\n\n\n\u003Cp>The natural choline supplement, BioCholine®, is a carefully controlled mixture of different plants well known in Ayurvedic medicine. The product is in powder form, which is thermostable and non-hygroscopic. It can be used in premixes and in pelletized or extruded feeds.\u003C\u002Fp>\n\n\n\n\u003Cp>The plants comprising BioCholine® provide choline in the form of phosphatidylcholine and other phospholipids, inositol, phosphatidylethanolamine and phosphatidylserine, important molecules for general metabolism. The experimental trials and the use of natural choline in the field over the last several years, in conventional production in Latin America and Europe, have proven that the product can totally substitute the choline chloride without any reduction in performance. BioCholine® can also improve performance with varying substitution ratios, due to the mode of action of the phosphatidylcholine and the synergistic interaction with the active components of the mix of plants. The recommended level of inclusion is between 1\u002F4 and 1\u002F5 of the dosage of choline chloride.\u003C\u002Fp>\n\n\n\n\u003Cp>Phosphatidylcholine, one of the active components of natural choline, acts as an agonist (promoter) of the PPARα (Peroxisome Proliferator Activated Receptors Alpha), proteic nuclear receptors acting on transcription processes. The PPARα regulate the expression of specific genes implicated in metabolic reactions, such as beta oxidation of fatty acids or regulation of energetic homeostasis due to the secretion of adiponectin.\u003C\u002Fp>\n\n\n\n\u003Cp>It has been demonstrated that PPARα are present both in the intestine and in the liver, indicating that natural choline (phosphatidylcholine) begins to act in the enterocytes and, later, in the liver, optimizing the absorption of nutrients in the diets and improving feed conversion and other productive parameters.\u003C\u002Fp>\n\n\n\n\u003Cp>Below are presented some study results with supplementation with BioCholine®:\u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\u003Cli>\u003Cstrong>Broilers\u003C\u002Fstrong>\u003Cul>\u003Cli>It has been demonstrated that 1kg of BioCholine® is equivalent to 4.8kg of choline chloride 60% in poultry\u003C\u002Fli>\u003Cli>In many experimental trials and in field conditions, supplementing BioCholine® has been shown to result in performances equal to or better than choline chloride in the promotion of optimal mobilization of fat, preventing the ‘fatty liver syndrome’\u003C\u002Fli>\u003Cli>The vegetal choline allows a greater utilization of the gross energy of the feed, enhancing apparent metabolizable energy levels and, consequently, feed conversion ratio and other productive parameters\u003C\u002Fli>\u003C\u002Ful>\u003C\u002Fli>\u003C\u002Ful>\n\n\n\n\u003Cul class=\"wp-block-list\">\u003Cli>\u003Cstrong>Layers\u003C\u002Fstrong>\u003Cul>\u003Cli>In older layers (75 weeks), natural choline improves the laying rate, weight of the eggs and the feed conversion ratio compared to choline chloride\u003C\u002Fli>\u003C\u002Ful>\u003C\u002Fli>\u003C\u002Ful>\n\n\n\n\u003Cul class=\"wp-block-list\">\u003Cli>\u003Cstrong>Swine\u003C\u002Fstrong>\u003Cul>\u003Cli>It has been demonstrated that 1kg of BioCholine® is equivalent to 6.3 kg of choline chloride 60% for pigs\u003C\u002Fli>\u003Cli>In recently weaned piglets, animals fed with herbaceous choline have greater daily weight gain, better feed conversion ratio and higher final weight compared to choline chloride\u003C\u002Fli>\u003C\u002Ful>\u003C\u002Fli>\u003C\u002Ful>\n\n\n\n\u003Cul class=\"wp-block-list\">\u003Cli>\u003Cstrong>Ruminants\u003C\u002Fstrong>\u003Cul>\u003Cli>In lambs, the vegetal choline presented results similar to that of rumen-protected choline in terms of daily weight gain and final weight\u003C\u002Fli>\u003Cli>Dairy sheep fed BioCholine® presented better weight at 30 days of lactation, increased fatty acid composition of milk (oleic acid) along with the same milk production and weight gain of lambs, compared to the by-pass choline\u003C\u002Fli>\u003Cli>In dairy cows, herbaceous choline demonstrated a significant increase in milk production and reduction of glycemia and β-hydroxybutyrate\u003C\u002Fli>\u003C\u002Ful>\u003C\u002Fli>\u003C\u002Ful>\n\n\n\n\u003Cp>Consistent positive results obtained in both monogastrics and ruminants reinforce that the use of BioCholine®, with strong experience in other markets, is an economical alternative to choline chloride, with a technical and scientific basis that guarantees a confident step forward in the changes that livestock production requires from the currently demanding markets.\u003C\u002Fp>\n","Supplementation with natural choline: myth or reality? - Nuproxa Switzerland Ltd",{"id":149,"filename":150,"path":151,"url":152,"alt_text":153,"title":13,"width":20,"height":21,"webp_url":154,"optimized_url":154,"thumbnail_url":155,"srcset":156,"srcset_webp":157,"responsive_images":158,"processing_status":34},753,"HEADER.png","assets\u002F2026\u002F04\u002Fheader-69e26833280d6.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6.png","Phytogenic research header in laboratory, Nuproxa natural feed additives R&D","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6-thumbnail.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6-thumbnail.png 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6-small.png 400w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6-medium.png 800w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6-large.png 1200w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6.png 1728w","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6-thumbnail.webp 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6-small.webp 400w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6-medium.webp 800w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6-large.webp 1200w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6.webp 1728w",{"large":159,"small":160,"medium":161,"thumbnail":155,"large_webp":162,"small_webp":163,"medium_webp":164,"thumbnail_webp":165},"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6-large.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6-small.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6-medium.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6-large.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6-small.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6-medium.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-69e26833280d6-thumbnail.webp",{"id":167,"filename":168,"path":169,"url":170,"alt_text":171,"title":172,"width":97,"height":98,"webp_url":173,"optimized_url":173,"thumbnail_url":174,"srcset":175,"srcset_webp":176,"responsive_images":177,"processing_status":34},560,"1-conteudo-1.png","assets\u002F2026\u002F03\u002F30c96e5d-0d1c-4741-8e8c-8d26c89e5f8a.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F30c96e5d-0d1c-4741-8e8c-8d26c89e5f8a.png","Corn crop content precision agriculture technology nutrients Nuproxa feed ingredients","Supplementation with natural choline: myth or reality? (thumb)","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F30c96e5d-0d1c-4741-8e8c-8d26c89e5f8a.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F30c96e5d-0d1c-4741-8e8c-8d26c89e5f8a-thumbnail.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F30c96e5d-0d1c-4741-8e8c-8d26c89e5f8a-thumbnail.png 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F30c96e5d-0d1c-4741-8e8c-8d26c89e5f8a.png 349w","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F30c96e5d-0d1c-4741-8e8c-8d26c89e5f8a-thumbnail.webp 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F30c96e5d-0d1c-4741-8e8c-8d26c89e5f8a.webp 349w",{"thumbnail":174,"thumbnail_webp":178},"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F30c96e5d-0d1c-4741-8e8c-8d26c89e5f8a-thumbnail.webp","2022-03-31T16:12:51+00:00",{"id":181,"name":182,"slug":183,"description":13},28,"Digestion","digestion",[185,186,190,191,195],{"id":181,"name":182,"slug":183,"description":13},{"id":187,"name":188,"slug":189,"description":13},56,"Pets","pets",{"id":117,"name":118,"slug":119,"description":13},{"id":192,"name":193,"slug":194,"description":13},72,"Ruminants","ruminants",{"id":58,"name":59,"slug":60,"description":13},[],{"id":198,"title":199,"slug":200,"alternate_slugs":201,"summary":202,"content":203,"meta_title":204,"meta_description":12,"focus_keyword":13,"featured_image":205,"thumbnail_image":223,"published_at":236,"category":237,"categories":238,"tags":245},59,"Importance of the use of liver protectors in the production output of broilers","importance-of-the-use-of-liver-protectors-in-the-production-output-of-broilers",{"en":200},"The liver is the organ performing the largest number of vital functions indispensable for the animal organism, most notably three that are especially relevant:","\n\u003Cp>\u003Cem>By: Sandra Olivera and Alfred Blanch.\u003C\u002Fem>\u003C\u002Fp>\n\n\n\n\u003Cp>The liver is the organ performing the largest number of vital functions indispensable for the animal organism, most notably three that are especially relevant:\u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\u003Cli>Detoxification: It acts as a filter that processes and eliminates toxins from waste produced by the metabolism itself, toxins and harmful chemicals from the environment and microorganisms that eliminated by Kupffer cells.\u003C\u002Fli>\u003Cli>Synthesis: It plays a highly important role in the digestion process and the metabolising of nutrients (carbohydrates, lipids and proteins) from the stimulation of bile acid synthesis.\u003C\u002Fli>\u003Cli>Storage: It is the main organ for storing energy from the organism, thanks to the high levels of glycogen (source of carbohydrates) and fat-soluble vitamins (A, D, E, K) that can be stored.\u003C\u002Fli>\u003C\u002Ful>\n\n\n\n\u003Cp>For all that, the liver plays a key role as the centre of a set of metabolic and productive activities, and its level of activity will be directly proportional to the level at which the metabolism works. This means that, during the animal’s growth in intensive production systems, the liver is potentially exposed to sustaining the damage caused by a wide variety of harmful substances, deriving from both the different metabolic processes (e.g. reactive oxygen species), and other external ones external to the organism itself (xenobiotic).2,3 As a result, under these conditions, the liver activity can be a limiting productivity factor. In this regard, the use of a hepatoprotective additive will prevent this activity from diminishing, significantly improving yield.\u003C\u002Fp>\n\n\n\n\u003Cp>Under these premises, there are two basic goals for using a hepatoprotective additive in the animals’ diet:\u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\u003Cli>Improving the integrity and regeneration of hepatocytes, optimising the liver’s ability to detoxify, enabling it to better counteract the harmful effects of mycotoxins, heavy metals, pesticides, antibiotics and other substances, as promoters of chemical growth, on the animals’ health and on their yield.\u003C\u002Fli>\u003Cli>Favouring liver synthesis by stimulating the activity of digestive enzymes that ensure optimum use of nutrients: carbohydrates, proteins, fats and fat-soluble vitamins, enhancing its intestinal absorption and, hence, their bioavailability.\u003C\u002Fli>\u003C\u002Ful>\n\n\n\n\u003Cp>\u003Cstrong>Types of hepatoprotective additives commercially available\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>Liver protectors act by protecting liver from toxins and stimulating its functions, which leads to improved animal health, growth and production.\u003C\u002Fp>\n\n\n\n\u003Cp>There are two different types available in the market:\u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\u003Cli>Herbal origin: made up of a combination of a variable number of herbs with different hepatoprotective properties, such as Phyllantus niruri, Azadirachta indica, Andrographis paniculata, Achyrantes aspera, etc.\u003C\u002Fli>\u003Cli>Donors of methyl groups: based on the methyl groups’ ability to connect to toxins, favouring their elimination from the animal.10 Compounds able to donate methyl groups most notably include certain amino acids and their derivatives (e.g. methionine, carnitine, betaine, etc.), vitamin derivatives (e.g. choline).\u003C\u002Fli>\u003C\u002Ful>\n\n\n\n\u003Cp>Both can come in liquid or powder form. Liquid liver protectors are added to drinking water and are generally used for healing purposes, as the poultry affected by liver problems normally significantly reduce their feed intake, while that is not the case with liquids. For other situations, when used for preventive purposes, powdered liquid protectors are the most commonly used, as they provide greater yield.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>Using a multi-herb blend as a liver protector\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>The effectiveness of a blend of four herbs with different hepatoprotective properties was evaluated; Phyllantus niruri, Azadirachta indica, Andrographis paniculata and Achyrantes aspera in 180 Ross roosters from a commercial farm which, at 20 days, were shipped to a specific unit, where they were subjected to different feeding programmes.\u003C\u002Fp>\n\n\n\n\u003Cp>The 180 animals were divided into 6 repetitions of 3 groups of 10 animals each:\u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\u003Cli>Group A (positive control): these were fed a normal diet.\u003C\u002Fli>\u003Cli>Group A (negative control): these were fed a normal diet supplemented with 10% oxidised soya oil and 0.5% ferrous sulphate.\u003C\u002Fli>\u003Cli>Group C: same diet as Group B, but supplemented with 250 g of a multi-herb blend per tonne of feed.\u003C\u002Fli>\u003C\u002Ful>\n\n\n\n\u003Cp>During the recovery phase (days 32 to 42), Groups A and B were fed a normal diet, while Group C was given a normal diet supplemented with 250 g of a multi-herb blend per tonne of feed.\u003C\u002Fp>\n\n\n\n\u003Cp>The study was conducted during the second growth period, spanning days 20 to 42. The chickens were weighed individually on days 20, 31 and 42, and their mortality was recorded daily. The feed intake and feed conversion ratio were measured on days 31 and 42. Blood tests and autopsies were also conducted (liver weight) on day 42 (Table 1). At the end of the study, blood samples were taken in order to evaluate differences between treatments regarding two serum markers of liver inflammation; Aspartate transaminase (AST) and Alkaline phosphatase (ALP). For the statistical study, an alpha risk of 5% was chosen.\u003C\u002Fp>\n\n\n\n\u003Cp>As shown in the results collected in Table 1, the addition of oxidised soya oil and high levels of ferrous sulphate in feed slightly, though not significantly, lowered growth yield. Supplementing with 250 g of multi-herb blend per tonne of feed significantly improved feed conversion and body weight during the intoxication stage (days 20 to 31), which could indicate that this multi-herb blend allowed the liver to use the oxidised soya oil as a source of energy.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>Conclusion\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>Optimisation in the use of feedstuffs and the increase in productivity are two of the most important aspects in the poultry industry. Due to the liver’s importance in digestion, absorption and metabolising of nutrients, the use of liver protectors that stimulate its ability to eliminate harmful substances, such as mycotoxins, heavy metals, pesticides, etc., and which allow the transportation and suitable use of nutrients to ensure an adequate valuation of the diet, will entail an improvement in the feed conversion ratio, in the efficiency of the development and in the production performance, while contributing toward maximising return on investment in the feed.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>References\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>1. Meyer S, Kulkarni A. Hepatotoxicity. In: Introduction to Biochemical Toxicology. New York: John Wiley and Sons; 2001.\u003C\u002Fp>\n\n\n\n\u003Cp>2. Halliwell B. Reactive oxygen species and the central nervous system. J Neurochem. 1992;59:1609–23.\u003C\u002Fp>\n\n\n\n\u003Cp>3. Halliwell B, Gutteridge J. Free Radicals in Biology and Medicine. Oxidative stress: Adaptation, damage, repair and death. 3rd ed UK Oxford Univ Press. 1999:246–350.\u003C\u002Fp>\n\n\n\n\u003Cp>4. Cubero FJ, Nieto N. Kupffer cells and alcoholic liver disease. Rev esp enferm. 2006;98:460-472.\u003C\u002Fp>\n\n\n\n\u003Cp>5. Sharon A. Overview of Hepatic Disease in Small Animals. MSD Man Merck Co, Inc, USA. 2016.\u003C\u002Fp>\n\n\n\n\u003Cp>6. Trivedi N, Rawal U. Hepatoprotective and antioxidant property of Andrographis paniculata (Nees) in BHC induced liver damage in mice. Indian J Exp Biol. 2001;39(1):41-46.\u003C\u002Fp>\n\n\n\n\u003Cp>7. Manjrekar A, Jisha V, Bag P, et al. Effect of P.niruri treatment on liver, kidney and testes in CLl4 induced hepatotoxic rats. Indian J Exp Biol. 2008;46(7):514-520.\u003C\u002Fp>\n\n\n\n\u003Cp>8. Mageswari B, Latha P, Rukkumani R. Effect of phyllanthus niruri on alcohol and polyunsaturated fatty acid induced oxidative stress in liver. Int J Pharm Pharm Sci. 2010;2(4):5862.\u003C\u002Fp>\n\n\n\n\u003Cp>9. Akbar S. Andrographis paniculata: a review of pharmacological activities and clinical effects. Altern Med Rev. 2011;16(1):66-77.\u003C\u002Fp>\n\n\n\n\u003Cp>10. Obeid R. The Metabolic Burden of Methyl Donor Deficiency with Focus on the Betaine Homocysteine Methyltransferase Pathway. Nutrients. 2013;5(9):3481–3495.\u003C\u002Fp>\n\n\n\n\u003Cp>11. McBreairty L, Robinson J, Harding S, Randell E, Brunton J, Bertolo R. Betaine is as effective as folate at re-synthesising methionine for protein synthesis during moderate methionine deficiency in piglets. Eur J Nutr. 2016;55(8):2423-2430.\u003C\u002Fp>\n\n\n\n\u003Cp>12. Hayat Z, Rehman A, Akram K, Farooq U, Saleem G. Evaluation of a natural methionine source on broiler growth performance. J Sci Food Agric. 2015;95(12):2462-6.\u003C\u002Fp>\n","Importance of the use of liver protectors in the production output of broilers - Nuproxa Switzerland Ltd",{"id":206,"filename":207,"path":208,"url":209,"alt_text":210,"title":13,"width":20,"height":21,"webp_url":211,"optimized_url":211,"thumbnail_url":212,"srcset":213,"srcset_webp":214,"responsive_images":215,"processing_status":34},755,"HEADER (2).png","assets\u002F2026\u002F04\u002Fheader-2-69e2692661a85.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F04\u002Fheader-2-69e2692661a85.png","Modern poultry house header with feeders, Nuproxa poultry production animal 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Nuproxa news broilers farm poultry industry animal nutrition production","Importance of the use of liver protectors in the production output of broilers (thumb)","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F2a2f4678-e6b3-4c1d-9c7e-1430b344bf49.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F2a2f4678-e6b3-4c1d-9c7e-1430b344bf49-thumbnail.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F2a2f4678-e6b3-4c1d-9c7e-1430b344bf49-thumbnail.png 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F2a2f4678-e6b3-4c1d-9c7e-1430b344bf49.png 349w","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F2a2f4678-e6b3-4c1d-9c7e-1430b344bf49-thumbnail.webp 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F2a2f4678-e6b3-4c1d-9c7e-1430b344bf49.webp 349w",{"thumbnail":231,"thumbnail_webp":235},"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F2a2f4678-e6b3-4c1d-9c7e-1430b344bf49-thumbnail.webp","2022-03-31T16:11:20+00:00",{"id":52,"name":53,"slug":54,"description":13},[239,240,244],{"id":52,"name":53,"slug":54,"description":13},{"id":241,"name":242,"slug":243,"description":13},34,"Health","health",{"id":117,"name":118,"slug":119,"description":13},[],{"id":117,"title":247,"slug":248,"alternate_slugs":249,"summary":250,"content":251,"meta_title":252,"meta_description":12,"focus_keyword":13,"featured_image":253,"thumbnail_image":270,"published_at":283,"category":284,"categories":285,"tags":288},"Efficient solutions and better results","efficient-solutions-and-better-results",{"en":248},"Pig farming is constantly changing. Since its technification in the 1970s, new knowledge and technologies are constantly being added to the farm routine","\n\u003Cp>Pig farming is constantly changing. Since its technification in the 1970s, new knowledge and technologies are constantly being added to the farm routine. \u003C\u002Fp>\n\n\n\n\u003Cp>The technification of pig farming started in Europe in the 1970s (SESTI, L.A.C.; SOBESTIANSKY, 1998), through intensification of the activity by adopting management that sought efficiency in terms of producing more quantity (kg of meat) with fewer resources (space, time, labor, feed, etc.). \u003C\u002Fp>\n\n\n\n\u003Cp>Obtaining an excellent productivity with continuous improvements and identifying the limiting causes for these indices to be reached became fundamental for producers and technicians linked to pig farming. Thus, indices such as feed conversion ratio (FC), daily weight gain (DWG), carcass yield (CR), absence of diseases and low mortality in all phases of production have always been considered critical in modern pig farming.\u003C\u002Fp>\n\n\n\n\u003Cp>In these phases it is desired that the pig gains the maximum weight in the shortest possible time, consuming the minimum amount of feed (MORÉS; AMARAL, 2001). Accelerated weight gain means achieving slaughter weight in the shortest possible time and, in this way, the producer achieves a return on his investment in the shortest possible time (VOS; DEWEY; FRIENDSHIP, 2000).\u003C\u002Fp>\n\n\n\n\u003Cdiv class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n\u003Cdiv class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n\u003Cfigure class=\"wp-block-image size-full\">\u003Cimg src=\"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F33d98d7f-d2a2-4fd6-bac7-0695273601df.webp\" srcset=\"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F33d98d7f-d2a2-4fd6-bac7-0695273601df-small.webp 400w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F33d98d7f-d2a2-4fd6-bac7-0695273601df.webp 650w\" alt=\"Blog inline image\" width=\"650\" height=\"682\" loading=\"lazy\">\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\n\n\u003Cdiv class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n\u003Cp>However, quantity is no longer the only factor to consider. The quality of the meat and the way the animals are reared (and fed) became decisive factors for consumers when choosing a product in the market. All this within the legal framework of each country, which in many cases limits or prohibits the use of practices\u002Fproducts that could be considered unethical. In these phases it is desired that the pig gains the maximum weight in the shortest possible time, consuming the minimum amount of feed (MORÉS; AMARAL, 2001).\u003C\u002Fp>\n\u003C\u002Fdiv>\n\u003C\u002Fdiv>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">Meat\u003C\u002Fh2>\n\n\n\n\u003Cp>The consumer considers the following as indicators of pork quality: appearance, color, smell, taste, tenderness, amount of fat, etc. Pigs accumulate fat under the skin in the dorsal region. This deposition expressed in millimeters of thickness is a criterion to differentiate carcasses as lean or fatty. The market demands leaner carcasses with less back fat. To achieve this, Ractopamine, a β-adrenergic that reverses the rate of fat and muscle deposition in pigs close to slaughter, was used for a long time, resulting in less fat deposition at this stage and greater availability of nutrients for muscle formation. However, the use of this molecule is currently banned in the European market and the industry is looking for alternatives to its use.\u003C\u002Fp>\n","Efficient solutions and better results - Nuproxa Switzerland Ltd",{"id":254,"filename":255,"path":256,"url":257,"alt_text":13,"title":13,"width":20,"height":21,"webp_url":258,"optimized_url":258,"thumbnail_url":259,"srcset":260,"srcset_webp":261,"responsive_images":262,"processing_status":34},777,"HEADER (16).png","assets\u002F2026\u002F05\u002Fheader-16-6a187a7d762ee.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-16-6a187a7d762ee.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-16-6a187a7d762ee.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-16-6a187a7d762ee-thumbnail.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fheader-16-6a187a7d762ee-thumbnail.png 150w, 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chick close-up early phase poultry health animal nutrition Nuproxa brooding","Efficient solutions and better results (thumb)","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F9c03fce9-4331-4aca-8a4f-a87ea97f8a12.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F9c03fce9-4331-4aca-8a4f-a87ea97f8a12-thumbnail.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F9c03fce9-4331-4aca-8a4f-a87ea97f8a12-thumbnail.png 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F9c03fce9-4331-4aca-8a4f-a87ea97f8a12.png 349w","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F9c03fce9-4331-4aca-8a4f-a87ea97f8a12-thumbnail.webp 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F9c03fce9-4331-4aca-8a4f-a87ea97f8a12.webp 349w",{"thumbnail":278,"thumbnail_webp":282},"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F03\u002F9c03fce9-4331-4aca-8a4f-a87ea97f8a12-thumbnail.webp","2022-03-24T12:30:46+00:00",{"id":52,"name":53,"slug":54,"description":13},[286,287],{"id":52,"name":53,"slug":54,"description":13},{"id":58,"name":59,"slug":60,"description":13},[],{"data":290},[291,346,390,436,456,499],{"id":292,"title":293,"slug":294,"alternate_slugs":295,"summary":298,"content":299,"meta_title":300,"meta_description":301,"focus_keyword":115,"featured_image":302,"thumbnail_image":320,"published_at":334,"category":335,"categories":336,"tags":345},133,"Who makes up the starting lineup of intelligent nutrition?","nuproxa-selection",{"pt":296,"en":294,"latam":297},"selecao-nuproxa","seleccion-nuproxa","The article presents Nuproxa's portfolio as a \"team\" of solutions and technical programs for animal nutrition, using a football team metaphor in which each product plays a specific role. It details the roles of NuxaSan, LivoLiv, Natu-B4, NuxaFen, C-Power, Neotegra, iNuxA-B4, and iNuxA-VC, covering metabolism, gut health, antioxidant protection, stress response, liver health, and aquaculture. It then describes the technical support programs (NAP Swine, NAP Poultry, and GHP), which turn field data into decisions to improve performance, profitability, and sustainability across poultry, swine, ruminant, fish, and shrimp production.","\u003Cp>\u003Cem>The Nuproxa Team and the technical support behind results in animal production.\u003C\u002Fem>\u003C\u002Fp>\u003Cp>In \u003Cstrong>animal production\u003C\u002Fstrong>, no consistent result comes from a single play. Just like in a great team, every role matters. Some players hold the defense, some organize the strategy, some accelerate performance, some respond to moments of pressure, and some help maintain energy efficiency.\u003C\u002Fp>\u003Cp>\u003Cstrong>This is the logic behind the Nuproxa Team\u003C\u002Fstrong>: a portfolio of naturally intelligent solutions and specialized technical programs developed to support different nutritional and production challenges.\u003C\u002Fp>\u003Cp>We are not talking only about products, but about a true team that brings together applied science, field experience, technical validation, and specialized support to help producers, nutritionists, formulators, and partners make more efficient, reliable, and profitable decisions.\u003C\u002Fp>\u003Ch2>A complete lineup for different animal production challenges\u003C\u002Fh2>\u003Cp>Poultry, swine, ruminant, fish, and shrimp production face challenges related to metabolism, gut health, stress, feed efficiency, quality, profitability, and sustainability. That is why relying on a single solution is not always enough.\u003C\u002Fp>\u003Cp>\u003Cstrong>It is necessary to build a consistent strategy rather than respond to challenges one at a time.\u003C\u002Fstrong>\u003C\u002Fp>\u003Cp>In the Nuproxa Team, every starter has a specific role within this nutritional strategy. \u003Cstrong>And they all share a common goal\u003C\u002Fstrong>: to contribute to smarter programs aligned with the real needs of each species and production system.\u003C\u002Fp>\u003Ch2>NuxaSan™: the defense for challenging moments\u003C\u002Fh2>\u003Cp>Every team needs a defense prepared to respond during moments of greater pressure.\u003C\u002Fp>\u003Cp>\u003Cstrong>In the Nuproxa Team, NuxaSan™ plays this role\u003C\u002Fstrong> by contributing as a productive performance enhancer in situations associated with protozoal challenges, supporting more efficient nutritional programs.\u003C\u002Fp>\u003Cp>Its role is especially relevant when the objective is to sustain productive response and strengthen efficiency-focused strategies through phytogenic compounds recognized for helping maintain the balance of the intestinal microbiota.\u003C\u002Fp>\u003Ch2>\u003Cstrong>LivoLiv Meta™: the team’s metabolic accelerator\u003C\u002Fstrong>\u003C\u002Fh2>\u003Cp>In a high-performing team, energy makes a difference.\u003C\u002Fp>\u003Cp>\u003Cstrong>LivoLiv Meta™ joins this lineup as a natural metabolic accelerator,\u003C\u002Fstrong> developed to support liver function, promote nutrient utilization, and optimize productive performance in poultry, swine, and ruminants.\u003C\u002Fp>\u003Cp>Its action contributes to liver health, metabolic response, and nutritional efficiency, all of which are fundamental in intensive production systems. When metabolism performs better, the nutritional strategy gains greater strength to transform formulation into results.\u003C\u002Fp>\u003Ch2>Natu-B4®: efficiency to turn energy into results\u003C\u002Fh2>\u003Cp>In a high-performing team, making the most of every resource makes all the difference.\u003C\u002Fp>\u003Cp>In the Nuproxa Team, \u003Cstrong>Natu-B4® contributes to this goal by acting as a natural modulator of energy metabolism\u003C\u002Fstrong>, supporting the efficient utilization of nutrients and energy by animals.\u003C\u002Fp>\u003Cp>More than a natural alternative to choline chloride, Natu-B4® supports nutritional programs focused on metabolic efficiency and productive performance, helping transform nutrition into consistent results.\u003C\u002Fp>\u003Ch2>NuxaFen™: the antioxidant protection specialist\u003C\u002Fh2>\u003Cp>Every team needs players capable of maintaining consistency even under challenging conditions.\u003C\u002Fp>\u003Cp>\u003Cstrong>NuxaFen™ harnesses the natural antioxidant potential of polyphenols\u003C\u002Fstrong> to support productivity, performance, and animal well-being. Its action helps reduce the effects of oxidative stress. In practice, it is a starter that contributes to greater formulation flexibility, economic efficiency, and support for the quality of animal-derived products.\u003C\u002Fp>\u003Ch2>C-Power™: the strength of the team in moments of pressure\u003C\u002Fh2>\u003Cp>In intensive production systems, moments of pressure are part of the routine.\u003C\u002Fp>\u003Cp>Heat, stocking density, metabolic challenges, management practices, and other factors can impact animal well-being, productivity, and efficiency. It is in this scenario that C-Power™ stands out.\u003C\u002Fp>\u003Cp>\u003Cstrong>As an anti-stress polyherbal complex\u003C\u002Fstrong> with natural antioxidant action and high bioavailability, C-Power™ was developed to help animals respond better to uncontrollable stress factors, supporting performance, feed efficiency, and productive response.\u003C\u002Fp>\u003Ch2>iNuxA-B4®: more than choline, a strategy for efficiency in aquaculture\u003C\u002Fh2>\u003Cp>Some starters stand out because they go beyond their traditional role.\u003C\u002Fp>\u003Cp>\u003Cstrong>iNuxA-B4® is an innovative solution for feed and premix formulation\u003C\u002Fstrong>, especially designed for aquaculture. More than a natural source of choline, it offers a 100% natural alternative to choline chloride in fish and shrimp diets.\u003C\u002Fp>\u003Cp>Its value proposition combines important formulation advantages, such as stability, lower hygroscopicity, low inclusion rates, and better use of space in premixes and feeds.\u003C\u002Fp>\u003Ch2>iNuxA-VC®: antioxidant support and efficiency for aquaculture\u003C\u002Fh2>\u003Cp>In aquaculture, performance also depends on adequate nutritional support for health, antioxidant response, and animal resilience.\u003C\u002Fp>\u003Cp>\u003Cstrong>iNuxA-VC® is a natural and highly bioavailable analog form of vitamin C\u003C\u002Fstrong>, developed for fish and shrimp. Its purpose is to replace monophosphate vitamin C, offering greater stability, high bioavailability, and additional benefits for health and performance.\u003C\u002Fp>\u003Cp>Among its key advantages are extrusion resistance, stability at high temperatures, low inclusion rates per ton of feed, and support for immune response, protection against oxidative stress, and regeneration processes.\u003C\u002Fp>\u003Ch2>The support that strengthens the team\u003C\u002Fh2>\u003Cp>\u003Cstrong>A great lineup needs more than just good starters.\u003C\u002Fstrong>\u003C\u002Fp>\u003Cp>It also needs technical insight, follow-up, data, and strategies that can be applied to the reality of each production system. This is where Nuproxa's programs come into play.\u003C\u002Fp>\u003Cp>They work as the support that strengthens the team: helping transform field information into more precise decisions and nutritional programs that are better aligned with production goals.\u003C\u002Fp>\u003Ch2>Technical Assistance Program for more efficient swine production\u003C\u002Fh2>\u003Cp>\u003Cstrong>The \u003Ca target=\"_blank\" rel=\"noopener noreferrer nofollow\" href=\"https:\u002F\u002Fnuproxa.ch\u002Fnap-swine\">NAP Nuproxa Assistance Program for Swine\u003C\u002Fa>\u003C\u002Fstrong> was developed to support modern swine production through technical support and nutritional follow-up.\u003C\u002Fp>\u003Cp>The program considers challenges related to management, animal welfare, health, nutrition, and sustainability, helping identify opportunities for improvement and strengthen customized intelligent nutrition programs.\u003C\u002Fp>\u003Cp>NAP Swine contributes to a more integrated view of production, with a focus on efficiency, productivity, and cost reduction.\u003C\u002Fp>\u003Ch2>Technical Assistance Program for poultry: data, performance, and applied intelligence\u003C\u002Fh2>\u003Cp>In poultry production, high performance requires technical control, continuous follow-up, and decisions based on reliable information.\u003C\u002Fp>\u003Cp>\u003Cstrong>The \u003Ca target=\"_blank\" rel=\"noopener noreferrer nofollow\" href=\"https:\u002F\u002Fnuproxa.ch\u002Fnap-poultry\">NAP Technical Assistance Program for Poultry\u003C\u002Fa>\u003C\u002Fstrong> was created to provide specialized technical support, data analysis, monitoring of nutrition and production program performance, identification of bottlenecks, and opportunities throughout the production chain.\u003C\u002Fp>\u003Cp>Its role is to support poultry companies seeking greater profitability, zootechnical performance, and strategic production management.\u003C\u002Fp>\u003Ch2>GHP: Gut and Hepatic Health Program for maximum performance\u003C\u002Fh2>\u003Cp>\u003Cstrong>The \u003Ca target=\"_blank\" rel=\"noopener noreferrer nofollow\" href=\"https:\u002F\u002Fnuproxa.ch\u002Fghp\">Gut Hepatic Health Program\u003C\u002Fa> is Nuproxa's technical-scientific program\u003C\u002Fstrong> focused on the diagnosis, monitoring, and optimization of gut and liver health, especially in broilers and other poultry production species.\u003C\u002Fp>\u003Cp>Through field evaluations, laboratory analyses, and data interpretation, GHP transforms complex information into practical decisions that support zootechnical performance, profitability, and health security.\u003C\u002Fp>\u003Cp>Its approach helps identify digestive alterations, evaluate nutritional and health programs, monitor animal response, and support more precise strategies in the field.\u003C\u002Fp>\u003Cp>\u003Cstrong>The right lineup makes a difference.\u003C\u002Fstrong>\u003C\u002Fp>\u003Cp>\u003Cstrong>In modern animal production, every decision matters.\u003C\u002Fstrong>\u003C\u002Fp>\u003Cp>Choosing a solution is not just about selecting a product. It is about defining the role it will play within a broader nutritional strategy connected to the challenges of the species, the production system, and performance objectives.\u003C\u002Fp>\u003Cp>\u003Cstrong>That is why the Nuproxa Team brings together starters with complementary roles\u003C\u002Fstrong>: solutions that support metabolism, gut integrity, antioxidant support, stress response, liver health, aquaculture, and productive performance, along with technical programs that help transform data into decisions.\u003C\u002Fp>\u003Cp>\u003Cstrong>Get to know the Nuproxa Team and discover how each starter can support your nutritional strategy\u003C\u002Fstrong>: \u003Ca target=\"_blank\" rel=\"noopener noreferrer nofollow\" href=\"https:\u002F\u002Fnuproxa.ch\u002F\">https:\u002F\u002Fnuproxa.ch\u002F\u003C\u002Fa>\u003C\u002Fp>","Nuproxa Team: Intelligent Animal Nutrition Lineup","Discover the Nuproxa Team of solutions and technical programs for intelligent animal nutrition in poultry, swine, ruminants, fish, and shrimp production.",{"id":303,"filename":304,"path":305,"url":306,"alt_text":307,"title":12,"width":20,"height":21,"webp_url":308,"optimized_url":308,"thumbnail_url":309,"srcset":310,"srcset_webp":311,"responsive_images":312,"processing_status":34},786,"01KVWVSRBDB04PTG6MX42136DA.png","gallery\u002F01KVWVSRBDB04PTG6MX42136DA.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVWVSRBDB04PTG6MX42136DA.png","Blurred background of a football stadium with grass field and stands","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVWVSRBDB04PTG6MX42136DA.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVWVSRBDB04PTG6MX42136DA-thumbnail.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVWVSRBDB04PTG6MX42136DA-thumbnail.png 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVWVSRBDB04PTG6MX42136DA-small.png 400w, 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product bags in blue, green, pink, and gray on podiums on a football field, each with a five-star rating",350,250,"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVWVTFQ48JGBNZ5CAWZ2D34F.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVWVTFQ48JGBNZ5CAWZ2D34F-thumbnail.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVWVTFQ48JGBNZ5CAWZ2D34F-thumbnail.png 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVWVTFQ48JGBNZ5CAWZ2D34F.png 350w","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVWVTFQ48JGBNZ5CAWZ2D34F-thumbnail.webp 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVWVTFQ48JGBNZ5CAWZ2D34F.webp 350w",{"thumbnail":329,"thumbnail_webp":333},"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVWVTFQ48JGBNZ5CAWZ2D34F-thumbnail.webp","2026-06-24T13:25:15+00:00",{"id":107,"name":108,"slug":109,"description":13},[337,338,342],{"id":107,"name":108,"slug":109,"description":13},{"id":339,"name":340,"slug":341,"description":13},43,"Notícias","noticias-pt",{"id":65,"name":343,"slug":344,"description":13},"Noticias","noticias-latam",[],{"id":347,"title":348,"slug":349,"alternate_slugs":350,"summary":351,"content":352,"meta_title":353,"meta_description":351,"focus_keyword":354,"featured_image":355,"thumbnail_image":373,"published_at":385,"category":386,"categories":387,"tags":389},132,"Intestinal Integrity: natural and smart solutions for high-performance poultry production","coccidiosis-natural-solutions",{"en":349},"Coccidiosis: natural and effective solutions as an alternative to anticoccidials to optimize poultry production.","\u003Cp>\u003Cstrong>Coccidiosis\u003C\u002Fstrong> remains one of the main challenges in poultry production. This intestinal disease, caused by protozoa of the genus \u003Cem>Eimeria\u003C\u002Fem> spp., affects the performance and health of poultry, resulting in considerable economic losses.\u003C\u002Fp>\u003Cp>Faced with this problem, producers are seeking natural and effective alternatives to maintain their birds' intestinal health without resorting to conventional options.\u003C\u002Fp>\u003Ch2>Challenges of coccidiosis and the role of anticoccidials\u003C\u002Fh2>\u003Cp>\u003Cstrong>Coccidiosis\u003C\u002Fstrong> causes severe damage to the intestinal epithelium, affecting nutrient absorption and weakening the birds' immune system. If left uncontrolled, it can cause:\u003C\u002Fp>\u003Cul>\u003Cli>\u003Cp>Reduced growth and body weight;\u003C\u002Fp>\u003C\u002Fli>\u003Cli>\u003Cp>Increased feed conversion ratios (FCR);\u003C\u002Fp>\u003C\u002Fli>\u003Cli>\u003Cp>High mortality in cases of severe outbreaks.\u003C\u002Fp>\u003C\u002Fli>\u003C\u002Ful>\u003Cp>\u003Cstrong>Synthetic anticoccidials\u003C\u002Fstrong> play an important role in controlling coccidiosis, but they present challenges that encourage the search for \u003Ca target=\"_blank\" rel=\"noopener noreferrer nofollow\" href=\"https:\u002F\u002Fnuproxa.ch\u002Fen\u002Fcoccidiosis-reduction-combined-strategies\u002F\">alternative solutions\u003C\u002Fa> focused on intestinal integrity and performance. These solutions help prevent and control the effects of \u003Cem>Eimeria\u003C\u002Fem> spp., minimizing damage to the intestinal tract and improving the birds' overall performance.\u003C\u002Fp>\u003Cp>The choice of the appropriate \u003Cstrong>anticoccidial\u003C\u002Fstrong> depends on the management strategy adopted by each producer, with a focus on maintaining long-term efficacy and preventing resistance. However, the trend toward safer and more sustainable solutions has driven the use of products based on phytochemicals, which optimize intestinal health naturally and efficiently.\u003C\u002Fp>\u003Ch2>Anticoccidials: factors affecting their effectiveness in poultry production\u003C\u002Fh2>\u003Cp>The use of \u003Cstrong>anticoccidials\u003C\u002Fstrong> is one of the most common strategies for \u003Ca target=\"_blank\" rel=\"noopener noreferrer nofollow\" href=\"https:\u002F\u002Fnuproxa.ch\u002Fen\u002Fcoccidiosis-treatment\u002F\">controlling coccidiosis in poultry production\u003C\u002Fa>. However, several factors can compromise their effectiveness and performance. From dosing issues to resistance due to prolonged use, it is essential to understand how to optimize the use of these products.\u003C\u002Fp>\u003Cp>\u003Cstrong>In our detailed blog post, we explore five key factors that affect the efficiency of anticoccidial drugs and how to overcome these challenges:\u003C\u002Fstrong>\u003C\u002Fp>\u003Cul>\u003Cli>\u003Cp>Causes of anticoccidial compound toxicity;\u003C\u002Fp>\u003C\u002Fli>\u003Cli>\u003Cp>Use of ionophores and nicarbazin;\u003C\u002Fp>\u003C\u002Fli>\u003Cli>\u003Cp>Development of resistance in coccidia;\u003C\u002Fp>\u003C\u002Fli>\u003Cli>\u003Cp>Loss of drug sensitivity;\u003C\u002Fp>\u003C\u002Fli>\u003Cli>\u003Cp>Sanitary conditions and farm management.\u003C\u002Fp>\u003C\u002Fli>\u003C\u002Ful>\u003Cp>Learn more about these factors and access our exclusive material with practical recommendations to maximize \u003Cstrong>coccidiosis control\u003C\u002Fstrong>.\u003C\u002Fp>\u003Cp>\u003Ca target=\"_blank\" rel=\"noopener noreferrer nofollow\" href=\"https:\u002F\u002Fnuproxa.ch\u002Fanticoccidial-medications\">\u003Cstrong>[Read the full blog post here]\u003C\u002Fstrong>\u003C\u002Fa>\u003C\u002Fp>\u003Ch2>A smart solution for intestinal health and performance support\u003C\u002Fh2>\u003Cp>NuxaSan™ is a state-of-the-art polyherbal solution that offers a natural, effective, and smart solution to help address challenges related to gut welfare. Its exclusive formulation combines Ayurvedic wisdom with modern science, providing unmatched benefits that support avian gut health.\u003C\u002Fp>\u003Ch3>Key benefits of the phytocompounds found on NuxaSan™\u003C\u002Fh3>\u003Cul>\u003Cli>\u003Cp>\u003Cstrong>Integrity:\u003C\u002Fstrong> Thanks to its rich composition of selected phytocompounds (saponins and tannins), it helps maintain intestinal health and contributes to the natural and effective management of problems of the gut environment during challenges.\u003C\u002Fp>\u003C\u002Fli>\u003Cli>\u003Cp>\u003Cstrong>Optimized poultry performance:\u003C\u002Fstrong> It helps maintain zootechnical performance in challenging situations by contributing to the maintenance of the intestinal wall and improvement of nutrient absorption.\u003C\u002Fp>\u003C\u002Fli>\u003Cli>\u003Cp>\u003Cstrong>Contributing to antioxidant function and gut welfare:\u003C\u002Fstrong> Tannins and saponins are known to contribute to host immunity and antioxidant function, promoting better intestinal resilience.\u003C\u002Fp>\u003C\u002Fli>\u003Cli>\u003Cp>\u003Cstrong>Certified safety and quality:\u003C\u002Fstrong> NuxaSan™ is a safe, residue-free solution manufactured under Nuproxa's globally recognized, certified feed safety management system, ensuring unparalleled quality for the poultry industry.\u003C\u002Fp>\u003C\u002Fli>\u003Cli>\u003Cp>\u003Cstrong>Vibrant pigmentation:\u003C\u002Fstrong> It contributes to skin and yolk pigmentation, improving the visual quality of the final products.\u003C\u002Fp>\u003C\u002Fli>\u003C\u002Ful>\u003Ch2>Why choose natural solutions for Gut Health?\u003C\u002Fh2>\u003Cp>In a market that prioritizes food safety and sustainability, natural solutions, such as NuxaSan™, stand out for delivering effective results without compromising the health of the end consumer or animal welfare. Furthermore, the absence of unwanted residues allows for its safe use in multi-species food production facilities.\u003C\u002Fp>\u003Ch2>Tangible results: the impact of NuxaSan™ on poultry production\u003C\u002Fh2>\u003Cp>Producing healthy poultry requires an integrated approach that includes quality nutrition and optimization of the gut microbiota. The phytocompounds in NuxaSan™ contribute significantly to:\u003C\u002Fp>\u003Cul>\u003Cli>\u003Cp>Improved nutrient absorption;\u003C\u002Fp>\u003C\u002Fli>\u003Cli>\u003Cp>Supporting the gut under challenges;\u003C\u002Fp>\u003C\u002Fli>\u003Cli>\u003Cp>Stronger, more productive birds with a balanced and resilient digestive system.\u003C\u002Fp>\u003C\u002Fli>\u003C\u002Ful>\u003Ch2>Optimize your birds' gut health with NuxaSan™\u003C\u002Fh2>\u003Cp>If you want to tackle intestinal \u003Cstrong>challenges\u003C\u002Fstrong> in a smart, natural, safe, and efficient way, NuxaSan™ is the ideal solution. Support your birds' performance and take your poultry production to the next level.\u003C\u002Fp>\u003Cp>\u003Cstrong>Talk to one of our Nuproxa experts and discover how NuxaSan™ can transform your business!\u003C\u002Fstrong>\u003C\u002Fp>","Smart Natural Solutions for Poultry Gut Integrity","anticoccidials",{"id":356,"filename":357,"path":358,"url":359,"alt_text":360,"title":12,"width":20,"height":21,"webp_url":361,"optimized_url":361,"thumbnail_url":362,"srcset":363,"srcset_webp":364,"responsive_images":365,"processing_status":34},785,"01KVRKGCBKECQ279T6F0DJ0998.png","gallery\u002F01KVRKGCBKECQ279T6F0DJ0998.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998.png","Coccidiosis: solutions for poultry production","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998-thumbnail.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998-thumbnail.png 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998-small.png 400w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998-medium.png 800w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998-large.png 1200w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998.png 1728w","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998-thumbnail.webp 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998-small.webp 400w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998-medium.webp 800w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998-large.webp 1200w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998.webp 1728w",{"thumbnail":362,"thumbnail_webp":366,"small":367,"small_webp":368,"medium":369,"medium_webp":370,"large":371,"large_webp":372},"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998-thumbnail.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998-small.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998-small.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998-medium.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998-medium.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998-large.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKGCBKECQ279T6F0DJ0998-large.webp",{"id":374,"filename":375,"path":376,"url":377,"alt_text":378,"title":12,"width":326,"height":327,"webp_url":379,"optimized_url":379,"thumbnail_url":380,"srcset":381,"srcset_webp":382,"responsive_images":383,"processing_status":34},784,"01KVRKD3BKXEN0QXZRRC1H4MQS.png","gallery\u002F01KVRKD3BKXEN0QXZRRC1H4MQS.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKD3BKXEN0QXZRRC1H4MQS.png","Natural solutions for coccidiosis","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKD3BKXEN0QXZRRC1H4MQS.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKD3BKXEN0QXZRRC1H4MQS-thumbnail.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKD3BKXEN0QXZRRC1H4MQS-thumbnail.png 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKD3BKXEN0QXZRRC1H4MQS.png 350w","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKD3BKXEN0QXZRRC1H4MQS-thumbnail.webp 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKD3BKXEN0QXZRRC1H4MQS.webp 350w",{"thumbnail":380,"thumbnail_webp":384},"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVRKD3BKXEN0QXZRRC1H4MQS-thumbnail.webp","2026-06-23T02:48:27+00:00",{"id":113,"name":114,"slug":115,"description":13},[388],{"id":113,"name":114,"slug":115,"description":13},[],{"id":391,"title":392,"slug":393,"alternate_slugs":394,"summary":395,"content":396,"meta_title":397,"meta_description":398,"focus_keyword":12,"featured_image":399,"thumbnail_image":417,"published_at":431,"category":432,"categories":433,"tags":435},131,"5 factors affecting the efficiency of anticoccidial medications in poultry production","anticoccidial-medications",{"en":393},"Control of coccidiosis is one of the greatest challenges in modern poultry production. Although anticoccidial medications are effective tools, several factors can directly impact their efficiency, ranging from resistance issues to management and dosing conditions. With this in mi...","\u003Cp>\u003Cstrong>Control of coccidiosis\u003C\u002Fstrong> is one of the greatest challenges in modern \u003Cstrong>poultry production\u003C\u002Fstrong>. Although \u003Cstrong>anticoccidial medications\u003C\u002Fstrong> are effective tools, several factors can directly impact their efficiency, ranging from resistance issues to management and dosing conditions.\u003C\u002Fp>\u003Cp>With this in mind, Nuproxa has developed a series of content aimed at guiding industry professionals on best practices and care in the use of these products. In previous articles, we explored the fundamentals and treatment methods for coccidiosis. Check them out:\u003C\u002Fp>\u003Cp>\u003Ca target=\"_blank\" rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fnuproxa.ch\u002Fen\u002Fcoccidiosis-in-poultry\u002F\">Coccidiosis in poultry: an ongoing challenge in poultry farming\u003C\u002Fa> \u003Cbr>\u003Ca target=\"_blank\" rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fnuproxa.ch\u002Fen\u002Fcoccidiosis-treatment\u002F\">Guide to the prevention and treatment of coccidiosis in poultry: part 1\u003C\u002Fa> \u003Cbr>\u003Ca target=\"_blank\" rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fnuproxa.ch\u002Fen\u002Fcoccidiosis-reduction-combined-strategies\u002F\">Combined and natural strategies to reduce the risk of coccidiosis in poultry\u003C\u002Fa>\u003C\u002Fp>\u003Cp>In this blog post, we will address five factors that directly affect the effectiveness of anticoccidial medications.\u003C\u002Fp>\u003Ch2>\u003Cstrong>1. Causes of intoxication by anticoccidial compounds\u003C\u002Fstrong>\u003C\u002Fh2>\u003Cp>Improper use or incorrect dosing of these compounds can lead to animal intoxication, affecting their development and performance (Novilla, 1992; Frigg et al., 1983). Causes include the inappropriate selection of medication for the production phase or undesirable interactions with other medications.\u003C\u002Fp>\u003Ch2>\u003Cstrong>2. Use of ionophores and nicarbazin\u003C\u002Fstrong>\u003C\u002Fh2>\u003Cp>Ionophore anticoccidials are widely used but require caution, as improper dosing can result in toxicity. (Novilla, 1992). Nicarbazin is widely used and often included in rotation programs with other products to reduce adverse effects (Ryley & Betts, 1973; Mathis & McDougald, 1982).\u003C\u002Fp>\u003Ch2>\u003Cstrong>3. Development of resistance by coccidia\u003C\u002Fstrong>\u003C\u002Fh2>\u003Cp>Resistance occurs when a medication is used repeatedly without rotation with other products. (Vertommen & Peek, 1994). This is a common issue in the industry, and the rotation of anticoccidials is recommended to reduce the risk.\u003C\u002Fp>\u003Ch2>\u003Cstrong>4. Loss of sensitivity to the medication\u003C\u002Fstrong>\u003C\u002Fh2>\u003Cp>Resistance develops when continuous administration or prolonged exposure to the same anticoccidial makes coccidia less sensitive to the medication (Ruff, 1993). This highlights the importance of the conscious and diversified use of these products.\u003C\u002Fp>\u003Ch2>\u003Cstrong>5. Farm conditions and risks for broilers\u003C\u002Fstrong>\u003C\u002Fh2>\u003Cp>Sanitary and management conditions on farms directly affect bird health and the effectiveness of medications (Graat et al., 1996; Henken, 1994). In farms with hygiene issues, the risk of subclinical coccidiosis is high, silently affecting bird performance.\u003C\u002Fp>\u003Ch3>\u003Cstrong>Conclusion\u003C\u002Fstrong>\u003C\u002Fh3>\u003Cp>In this context, it is necessary to understand the characteristics of \u003Cstrong>anticoccidial products\u003C\u002Fstrong>, their molecules, mechanisms of action, levels of toxicity, the different species of \u003Cstrong>\u003Cem>Eimeria\u003C\u002Fem>\u003C\u002Fstrong>, and the correct way to use them, ensuring results without compromising animal performance.\u003C\u002Fp>\u003Cp>To support this analysis in practice, you can rely on Nuproxa technical support. Through the \u003Cstrong>Gut and Hepatic Health Program (GHP)\u003C\u002Fstrong>, the team conducts field diagnostics, laboratory analyses, and continuous monitoring, generating data that support more confident decision-making in \u003Cstrong>poultry production\u003C\u002Fstrong>.\u003C\u002Fp>\u003Cp>Based on this information, it is possible to assess intestinal health, adjust nutritional strategies, and improve productive performance with greater predictability.\u003C\u002Fp>\u003Cp>\u003Cstrong>Contact Nuproxa to learn more: \u003C\u002Fstrong>\u003Ca target=\"_blank\" rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fnuproxa.ch\u002Fen\u002Fcontact\">https:\u002F\u002Fnuproxa.ch\u002Fen\u002Fcontact\u003C\u002Fa>\u003C\u002Fp>\u003Ch3> \u003Cbr>\u003Cstrong>References:\u003C\u002Fstrong>\u003C\u002Fh3>\u003Cp>Novilla, M. N. (1992). \u003Cem>The veterinary importance of the toxic syndrome induced by ionophores\u003C\u002Fem>. Veterinary and Human Toxicology, 34(1), 66–70.\u003C\u002Fp>\u003Cp>Frigg, M., Broz, J., & Weber, G. (1983). \u003Cem>Compatibility studies of ionophore anticoccidials with various antibiotics and chemotherapeutics in broiler chicks\u003C\u002Fem>. Archiv für Geflügelkunde, 47(5), 213–220.\u003C\u002Fp>\u003Cp>Ryley, J. F., & Betts, M. J. (1973). \u003Cem>Chemotherapy of chicken coccidiosis\u003C\u002Fem>. Advances in Pharmacology and Chemotherapy, 11, 221–293.\u003C\u002Fp>\u003Cp>Mathis, G. F., & McDougald, L. R. (1982). \u003Cem>Drug responsiveness of field isolates of chicken coccidia\u003C\u002Fem>. Poultry Science, 61, 38–45.\u003C\u002Fp>\u003Cp>Vertommen, M. H., & Peek, H. W. (1994). \u003Cem>How can we break resistance problems?\u003C\u002Fem> World Poultry, Special Supplement on Coccidiosis.\u003C\u002Fp>\u003Cp>Ruff, M. D. (1993). \u003Cem>The value of sensitivity testing in avian coccidiosis\u003C\u002Fem>. Avicultura Profesional, 10(3), 109–116.\u003C\u002Fp>\u003Cp>Graat, E. A. M. I. (1996). \u003Cem>Effects of initial litter contamination level with Eimeria acervulina on population dynamics and production characteristics in broilers\u003C\u002Fem>. Veterinary Parasitology, 165, 223–232.\u003C\u002Fp>\u003Cp>Henken, A. M. (1994). \u003Cem>Description of a simulation model for the population dynamics of Eimeria acervulina infection in broilers\u003C\u002Fem>. Parasitology, 108, 503–512.\u003C\u002Fp>\u003Cp>Williams, R. B. (1999). \u003Cem>A compartmentalised model for the estimation of the cost of coccidiosis to the world’s chicken production industry\u003C\u002Fem>. International Journal for Parasitology, 29, 1209–1229.\u003C\u002Fp>","5 factors affecting anticoccidial efficiency in poultry","Control of coccidiosis is one of the greatest challenges in modern poultry production. Although anticoccidial medications are effective tools, several factors c",{"id":400,"filename":401,"path":402,"url":403,"alt_text":12,"title":404,"width":20,"height":21,"webp_url":405,"optimized_url":405,"thumbnail_url":406,"srcset":407,"srcset_webp":408,"responsive_images":409,"processing_status":34},783,"01KVGP3M0P2K6MSADFAQJRA6G8.png","gallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8.png","Galpão de criação de frangos de corte com centenas de aves brancas sobre piso coberto de maravalha, alimentadores tubulares amarelos distribuídos em linhas e tubulações metálicas ao longo do ambiente.","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8-thumbnail.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8-thumbnail.png 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8-small.png 400w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8-medium.png 800w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8-large.png 1200w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8.png 1728w","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8-thumbnail.webp 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8-small.webp 400w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8-medium.webp 800w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8-large.webp 1200w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8.webp 1728w",{"thumbnail":406,"thumbnail_webp":410,"small":411,"small_webp":412,"medium":413,"medium_webp":414,"large":415,"large_webp":416},"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8-thumbnail.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8-small.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8-small.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8-medium.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8-medium.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8-large.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fgallery\u002F01KVGP3M0P2K6MSADFAQJRA6G8-large.webp",{"id":418,"filename":419,"path":420,"url":421,"alt_text":422,"title":13,"width":423,"height":424,"webp_url":425,"optimized_url":425,"thumbnail_url":426,"srcset":427,"srcset_webp":428,"responsive_images":429,"processing_status":34},770,"SM38_NUP_Thumb-300x214.png","assets\u002F2026\u002F05\u002Fsm38-nup-thumb-f5bc705f2c89.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fsm38-nup-thumb-f5bc705f2c89.png","Close-up of a white chicken in a poultry farm, illustrating coccidiosis control",300,214,"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fsm38-nup-thumb-f5bc705f2c89.webp","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fsm38-nup-thumb-f5bc705f2c89-thumbnail.png","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fsm38-nup-thumb-f5bc705f2c89-thumbnail.png 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fsm38-nup-thumb-f5bc705f2c89.png 300w","https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fsm38-nup-thumb-f5bc705f2c89-thumbnail.webp 150w, https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fsm38-nup-thumb-f5bc705f2c89.webp 300w",{"thumbnail":426,"thumbnail_webp":430},"https:\u002F\u002Fapi.nuproxa.ch\u002Fstorage\u002Fassets\u002F2026\u002F05\u002Fsm38-nup-thumb-f5bc705f2c89-thumbnail.webp","2026-04-24T22:12:31+00:00",{"id":113,"name":114,"slug":115,"description":13},[434],{"id":113,"name":114,"slug":115,"description":13},[],{"id":437,"title":438,"slug":439,"alternate_slugs":440,"summary":441,"content":442,"meta_title":443,"meta_description":444,"focus_keyword":445,"featured_image":446,"thumbnail_image":448,"published_at":450,"category":451,"categories":452,"tags":455},130,"Hepatic protector vs hepatic modulator in poultry: understand the differences","hepatic-protector-hepatic-modulator-in-poultry",{"en":439},"Hepatic health in poultry production is crucial for animal welfare, productivity, and zootechnical performance. Understand the differences between hepatic protectors and modulators.","\u003Cp>\u003Cstrong>Hepatic health in poultry\u003C\u002Fstrong> production is a crucial factor to ensure animal welfare, productivity, and zootechnical performance. The liver is a multifunctional organ responsible for essential metabolic processes, detoxification of substances, and support of the immune system. Therefore, preserving its function is a priority in intensive production systems. \u003C\u002Fp>\n\n\u003Cp>In this context, different products have been developed to help maintain liver function under optimal conditions and prevent disorders. Among them, two groups stand out: \u003C\u002Fp>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Hepatic protectors; \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Hepatic modulators. \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cp>Although both aim to support liver health, their approaches are different. Understanding these differences is essential for a strategic use in animal nutrition, according to the production phase and the challenges faced by the birds.  \u003Cbr> \u003C\u002Fp>\n\n\u003Cp>\u003Cstrong>What is a hepatic protector?\u003C\u002Fstrong> \u003C\u002Fp>\n\n\u003Cp>\u003Cstrong>Hepatic protectors\u003C\u002Fstrong> are substances designed to prevent liver damage and protect the functional integrity of the liver against challenges such as: \u003C\u002Fp>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Environmental toxins; \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Feed contaminants; \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Mycotoxins. \u003Cbr> \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cp>\u003Cstrong>These products usually contain a combination of:\u003C\u002Fstrong> \u003C\u002Fp>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Vitamins (such as vitamin E); \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Minerals (such as selenium); \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Amino acids (such as methionine); \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Plants with hepatoprotective properties (such as milk thistle and artichoke). \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cp>\u003Cstrong>These ingredients act synergistically to:\u003C\u002Fstrong> \u003C\u002Fp>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Strengthen liver defenses; \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Improve detoxification capacity; \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Reduce hepatic inflammation. \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cp>The use of \u003Cstrong>hepatic protectors \u003C\u002Fstrong>is especially recommended during periods of rapid growth, feed transitions, vaccination, and environmental stress, providing additional support to maintain optimal liver function and reduce the incidence of diseases. \u003C\u002Fp>\n\n\u003Cp>\u003Cstrong>Why is a hepatic modulator different from a hepatic protector?\u003C\u002Fstrong> \u003C\u002Fp>\n\n\u003Cp>Unlike protectors, which have a preventive role, \u003Cstrong>hepatic modulators in poultry\u003C\u002Fstrong> play a more active role in the physiological regulation of liver function. In other words, they not only contribute to protection but also help modulate liver processes, promoting more efficient function. \u003C\u002Fp>\n\n\u003Cp>\u003Cstrong>These products typically contain:\u003C\u002Fstrong> \u003C\u002Fp>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Plant extracts (such as rosemary and turmeric); \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Prebiotics and probiotics; \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Organic acids; \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Oligosaccharides. \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cp>By promoting the\u003Cstrong> balance of the intestinal microbiota\u003C\u002Fstrong>, they help improve digestion, nutrient absorption, and reduce the toxic load on the liver. \u003Cbr> \u003C\u002Fp>\n\n\u003Cp>\u003Cstrong>Among their physiological effects, the following stand out:\u003C\u002Fstrong> \u003C\u002Fp>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Regulation of hepatic enzymatic activity; \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Stimulation of cellular regeneration; \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Reduction of hepatic inflammation. \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cp>These mechanisms are particularly useful in situations of metabolic overload, allowing the liver to restore its optimal performance even after physiological challenges. \u003C\u002Fp>\n\n\u003Cp>\u003Cstrong>Conclusion\u003C\u002Fstrong> \u003C\u002Fp>\n\n\u003Cp>\u003Cstrong>Hepatic protectors and modulators in poultry \u003C\u002Fstrong>are strategic allies in maintaining liver health. Each product group offers specific benefits, and their selection should consider: \u003C\u002Fp>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Management conditions; \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Production phase; \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Health status of the flock; \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Zootechnical objectives. \u003C\u002Fli>\n\u003C\u002Ful>\n\n\u003Cp>While \u003Cstrong>hepatic protectors \u003C\u002Fstrong>mainly focus on preventing liver damage and preserving liver integrity, modulators go further by actively regulating liver function and contributing to improved intestinal health. In many cases, combining both types of products can be beneficial to maximize \u003Cstrong>poultry performance in modern production systems.\u003C\u002Fstrong> \u003C\u002Fp>\n\n\u003Cp>\u003Cstrong>Want to explore this evaluation further?\u003C\u002Fstrong> \u003C\u002Fp>\n\n\u003Cp>Talk to one of our technical specialists to understand how to adapt the use to your production reality: \u003Ca href=\"https:\u002F\u002Fnuproxa.ch\u002Fen\u002Fcontact\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">https:\u002F\u002Fnuproxa.ch\u002Fen\u002Fcontact\u002F\u003C\u002Fa> \u003C\u002Fp>\n\n\u003Cp>\u003Cstrong>An advanced solution from Nuproxa\u003C\u002Fstrong> \u003C\u002Fp>\n\n\u003Cp>Nuproxa offers \u003Ca href=\"https:\u002F\u002Fnuproxa.ch\u002Fen\u002Fproducts\u002Flivoliv\" target=\"_blank\" rel=\"noreferrer noopener\">Livoliv 250™\u003C\u002Fa>, a polyherbal product developed based on nutrigenomics, combining a complex set of phytoactives capable of supporting the modulation and acceleration of hepatic regeneration metabolism, helping promote optimal liver functionality and improve poultry performance. \u003C\u002Fp>\n\n\u003Cp>\u003Cstrong>\u003Cem>Source:\u003C\u002Fem>\u003C\u002Fstrong> \u003C\u002Fp>\n\n\u003Cp>\u003Cem>Nuproxa technical team. \u003C\u002Fem>\u003Cem>Entendiendo las diferencias entre un protector hepático y un modulador hepático en avicultura.\u003C\u002Fem> \u003C\u002Fp>","Hepatic protector vs. hepatic modulator in poultry farming","Hepatic protector vs. hepatic modulator in poultry farming: understand the differences for a strategic use in animal nutrition.","hepatic protector poultry",{"id":206,"filename":207,"path":208,"url":209,"alt_text":210,"title":13,"width":20,"height":21,"webp_url":211,"optimized_url":211,"thumbnail_url":212,"srcset":213,"srcset_webp":214,"responsive_images":447,"processing_status":34},{"large":216,"small":217,"medium":218,"thumbnail":212,"large_webp":219,"small_webp":220,"medium_webp":221,"thumbnail_webp":222},{"id":206,"filename":207,"path":208,"url":209,"alt_text":210,"title":13,"width":20,"height":21,"webp_url":211,"optimized_url":211,"thumbnail_url":212,"srcset":213,"srcset_webp":214,"responsive_images":449,"processing_status":34},{"large":216,"small":217,"medium":218,"thumbnail":212,"large_webp":219,"small_webp":220,"medium_webp":221,"thumbnail_webp":222},"2026-03-27T20:57:19+00:00",{"id":241,"name":242,"slug":243,"description":13},[453,454],{"id":241,"name":242,"slug":243,"description":13},{"id":117,"name":118,"slug":119,"description":13},[],{"id":241,"title":457,"slug":458,"alternate_slugs":459,"summary":460,"content":461,"meta_title":462,"meta_description":463,"focus_keyword":13,"featured_image":464,"thumbnail_image":481,"published_at":494,"category":495,"categories":496,"tags":498},"Natu-B4®: 22 years of innovation in natural choline with scientific validation","natural-choline-natu-b4",{"en":458},"The evolution of animal nutrition in recent decades has been marked by a constant search for production efficiency, safety, and sustainability. In this scenario, choline has established itself as a strategic nutrient, mainly due to its role in energy and lipid metabolism. Over the years, what has changed is the approach adopted to meet this nutritional demand.  From the outset, Nuproxa approach to the development of […]","\n\u003Cp>The evolution of \u003Cstrong>animal nutrition \u003C\u002Fstrong>in recent decades has been marked by a constant search for production efficiency, safety, and sustainability. In this scenario, choline has established itself as a strategic nutrient, mainly due to its role in \u003Cstrong>energy and lipid metabolism\u003C\u002Fstrong>. Over the years, what has changed is the approach adopted to meet this \u003Cstrong>nutritional demand\u003C\u002Fstrong>. \u003Cbr> \u003Cbr>From the outset, Nuproxa approach to the development of Natu-B4® focused on understanding and scientifically proving how a \u003Ca href=\"https:\u002F\u002Fnuproxa.ch\u002Fen\u002Fpolyherbal-products\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cstrong>polyherbal solution\u003C\u002Fstrong>\u003C\u002Fa> could act more broadly on animal metabolism, going beyond simply replacing synthetic \u003Ca href=\"https:\u002F\u002Fnuproxa.ch\u002Fen\u002Fnatural-alternative-choline-chloride\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cstrong>choline chloride\u003C\u002Fstrong>.\u003C\u002Fa>  \u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\" id=\"h-a-scientifically-based-polyherbal-innovation-nbsp\">\u003Cstrong>A scientifically based polyherbal innovation\u003C\u002Fstrong> \u003C\u002Fh2>\n\n\n\n\u003Cp id=\"h-a-scientifically-based-polyherbal-innovation-natu-b4-is-formulated-from-carefully-selected-plants-used-in-their-natural-form-without-chemical-extractions-among-the-species-used-are-solanum-nigrum-and-achyranthes-aspera-which-provide-natural-phospholipid-conjugates-such-as-phosphatidylcholine-in-addition-to-other-bioactive-compounds-characteristic-of-the-plant-matrix\">\u003Ca href=\"https:\u002F\u002Fnuproxa.ch\u002Fen\u002Fproducts\u002Fnatu-b4\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cstrong>Natu-B4®\u003C\u002Fstrong>\u003C\u002Fa> is formulated from carefully selected plants, used in their natural form, without chemical extractions. Among the species used are \u003Cem>Solanum nigrum \u003C\u002Fem>and \u003Cem>Achyranthes aspera\u003C\u002Fem>, which provide natural phospholipid conjugates, such as phosphatidylcholine, in addition to other bioactive compounds characteristic of the plant matrix.  \u003C\u002Fp>\n\n\n\n\u003Cp>Over more than 22 years of development, the product has been evaluated in more than 100 \u003Cem>in vivo \u003C\u002Fem>studies conducted at universities, research centers, and commercial facilities, involving more than 10 animal species.   \u003C\u002Fp>\n\n\n\n\u003Cp>This data set has resulted in the largest, \u003Cstrong>most diverse, and most complete scientific dossier in the natural choline segment\u003C\u002Fstrong>, reinforcing its position as the most validated solution on the market. \u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\" id=\"h-why-is-scientific-validation-a-distinguishing-feature-of-natural-choline-nbsp\">\u003Cstrong>Why is scientific validation a distinguishing feature of natural choline?\u003C\u002Fstrong> \u003C\u002Fh2>\n\n\n\n\u003Cp>One of \u003Cstrong>Natu-B4®\u003C\u002Fstrong>‘s most significant milestones is the \u003Cstrong>scientific proof\u003C\u002Fstrong> that supports its mode of action.   \u003C\u002Fp>\n\n\n\n\u003Cp>Studies described in Nuproxa technical materials show that the natural phospholipids present in \u003Cstrong>Natu-B4® are associated with the activation of metabolic\u003C\u002Fstrong> pathways related to PPAR-α (Peroxisome Proliferator-Activated Receptors), central regulators of fatty acid \u003Cstrong>metabolism and energy utilization\u003C\u002Fstrong>.  \u003C\u002Fp>\n\n\n\n\u003Cp>This metabolic approach differentiates \u003Cstrong>Natu-B4®\u003C\u002Fstrong> from conventional approaches, positioning it far beyond an\u003Cstrong> herbal choline\u003C\u002Fstrong>, but also as a natural \u003Cstrong>modulator of energy metabolism\u003C\u002Fstrong>, with consistent effects on nutrient utilization efficiency. \u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\" id=\"h-in-nbsp-which-species-has-the-effectiveness-of-natu-b4-been-proven-nbsp\">\u003Cstrong>In which species has the effectiveness of Natu-B4® been proven?\u003C\u002Fstrong> \u003C\u002Fh2>\n\n\n\n\u003Cp>Over more than two decades, studies conducted with Natu-B4® demonstrate its applicability in different production systems: \u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>\u003Cstrong>Poultry: \u003C\u002Fstrong>studies indicate that Natu-B4® can be used as an alternative to choline chloride, with beneficial effects observed on production parameters.\u003Cstrong> \u003C\u002Fstrong> \u003C\u002Fli>\n\u003C\u002Ful>\n\n\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>\u003Cstrong>Swine: \u003C\u002Fstrong>available data point to an association with energy use efficiency and growth profile. \u003C\u002Fli>\n\u003C\u002Ful>\n\n\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>\u003Cstrong>Ruminants:\u003C\u002Fstrong> the product’s plant matrix is resistant to ruminal degradation, allowing metabolic effects after the rumen. \u003C\u002Fli>\n\u003C\u002Ful>\n\n\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>\u003Cstrong>Pets: \u003C\u002Fstrong>nutrigenomics studies described in technical materials indicate modulation of metabolic pathways associated with lipid and energy metabolism. \u003C\u002Fli>\n\u003C\u002Ful>\n\n\n\n\u003Ch2 class=\"wp-block-heading\" id=\"h-technological-stability-quality-and-safety-nbsp\">\u003Cstrong>Technological stability, quality, and safety\u003C\u002Fstrong> \u003C\u002Fh2>\n\n\n\n\u003Cp>In addition to its \u003Cstrong>metabolic performance, Natu-B4®\u003C\u002Fstrong> offers significant technological advantages. Because it is integrated into the plant matrix, its active compounds demonstrate high stability, do not interact negatively with vitamins or pigments, and maintain their integrity even under adverse temperature and humidity conditions.  \u003C\u002Fp>\n\n\n\n\u003Cp>Nuproxa adopts rigorous sanitation processes, such as gamma irradiation or organic acid treatments, ensuring low levels of microbiological contamination. The entire product line is \u003Ca href=\"https:\u002F\u002Fnuproxa.ch\u002Fen\u002Ffami-qs-quality\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">FAMI-QS certified\u003C\u002Fa>, in addition to ISO 9001, 14001, and 18001 certifications, ensuring traceability, quality, and environmental commitment. \u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\" id=\"h-technical-nbsp-expertise-nbsp-as-part-of-the-solution-nbsp-nbsp\">\u003Cstrong>Technical expertise as part of the solution \u003C\u002Fstrong> \u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cstrong>Polyherbal formulations \u003C\u002Fstrong>require in-depth knowledge of raw materials, harvesting, processing, and the correct combination of plants. With over two decades of experience, Nuproxa has consolidated a technical and after-sales support model based on scientific documentation, consistent production, and close customer follow-up.  \u003C\u002Fp>\n\n\n\n\u003Cp>This set of factors reinforces that Natu-B4® is a nutritional solution built on applied knowledge and continuous validation. \u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\" id=\"h-conclusion-nbsp\">\u003Cstrong>Conclusion\u003C\u002Fstrong> \u003C\u002Fh3>\n\n\n\n\u003Cp>After 22 years of research, validation, and practical application, \u003Cstrong>Natu-B4®\u003C\u002Fstrong> has established itself as a benchmark in natural choline for animal nutrition. Its unique selling point goes beyond its plant origin and is reinforced by scientific proof of its mode of action, the robustness of its technical dossier, and the efficiency of its results.  \u003C\u002Fp>\n\n\n\n\u003Cp>In a scenario where innovation needs to be supported by evidence, Natu-B4® represents a mature, validated solution that is aligned with the current demands of animal production.  \u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\" id=\"h-want-nbsp-to-know-more-about-the-benefits-of-natu-b4-for-nbsp-your-animal-nbsp-production-nbsp\">\u003Cstrong>Want to know more about the benefits of Natu-B4® for your animal production?\u003C\u002Fstrong> \u003C\u002Fh3>\n\n\n\n\u003Cp>Visit the page for the market-leading solution that has 22 years of scientific validation: \u003Ca href=\"https:\u002F\u002Fnuproxa.ch\u002Fen\u002Fproducts\u002Fnatu-b4\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">https:\u002F\u002Fnuproxa.ch\u002Fen\u002Fproducts\u002Fnatu-b4\u002F\u003C\u002Fa>\u003Cstrong>\u003Cem>\u003C\u002Fem>\u003C\u002Fstrong> \u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>\u003Cem>Content developed from technical and scientific materials from Nuproxa\u003C\u002Fem>\u003C\u002Fstrong> \u003C\u002Fp>\n","Natu-B4®: 22 years of innovation in natural choline with scientific validation - Nuproxa Switzerland Ltd","Discover how Natu-B4®, with more than 22 years of scientific validation, has become a benchmark in natural choline for animal nutrition.",{"id":465,"filename":466,"path":467,"url":468,"alt_text":13,"title":13,"width":20,"height":21,"webp_url":469,"optimized_url":469,"thumbnail_url":470,"srcset":471,"srcset_webp":472,"responsive_images":473,"processing_status":34},773,"HEADER 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